Too much salt can disrupt the energy balance of immune cells and prevent them from functioning correctly.
The sense of taste in female mosquitoes is specially tuned to detect at least four different substances in blood.
The retrieval of mitochondria via a feedback loop is vital to sustaining synaptic transmission.
Researchers have identified a bio-chemical circuit that supports neuron-microglia communication. When neurons are active, they release ATP. Microglia sense extracellular ATP and the compound draws the immune cell toward the neuron.
Glial cells known as tanycytes deliver signals to neurons in the brain to activate appetite. Optogenetic stimulation of tanycytes increases appetite.
Microscopy study sheds light on the function of two calcium homeostasis modulators.
When a motor neuron-specific pool of heat shock protein 90 (Hps90) was inhibited, motor neuron apoptosis was triggered.
Using zebrafish models, researchers detected genes with altered levels of expression. The genetic variations were associated with abnormalities with mitochondrial function and the production of ATP.
Researchers have developed small molecules that inhibit one of the main enzymes implicated in autoimmune response. The research could lead to potential new medications for a range of autoimmune diseases.
Vitamin B12 significantly prevents the neurotoxicity of LRRK2 genetic variants associated with hereditary Parkinson's disease. The findings may help with the development of new therapies to combat the neurodegenerative disease.
Researchers depression and anxiety alters energy metabolism in the brain.
Removing the RCAN1 gene in mice reduced weight gain, even when the animals were fed high fat diets for prolonged periods of time. Researchers say the findings could help develop new treatments to help prevent obesity in humans.
