New insight into motor neuron death mechanisms could be a step toward ALS treatment
When a motor neuron-specific pool of heat shock protein 90 (Hps90) was inhibited, motor neuron apoptosis was triggered.... Read More...
ATP
Could a small fish prompt a leap forward for Alzheimer’s disease research?
Using zebrafish models, researchers detected genes with altered levels of expression. The genetic variations were associated with abnormalities with mitochondrial function and the production of ATP. ... Read More...
New compounds could be used to treat autoimmune disorders
Researchers have developed small molecules that inhibit one of the main enzymes implicated in autoimmune response. The research could lead to potential new medications for a range of autoimmune diseases.... Read More...
Vitamin B12 identified as the inhibitor of a key enzyme in hereditary Parkinson’s disease
Vitamin B12 significantly prevents the neurotoxicity of LRRK2 genetic variants associated with hereditary Parkinson's disease. The findings may help with the development of new therapies to combat the neurodegenerative disease. ... Read More...
Anxiety and Depressive Disorders Alter Brain Gene Activity
Researchers depression and anxiety alters energy metabolism in the brain.... Read More...
Gene that Lets You Eat As Much As You Like Holds Promise Against Obesity
Removing the RCAN1 gene in mice reduced weight gain, even when the animals were fed high fat diets for prolonged periods of time. Researchers say the findings could help develop new treatments to help prevent obesity in humans.... Read More...
The Brain’s Tiny Thrill Seekers
Researchers discover numerous differences in microglia between males and females. In males, the study reports, microglia is more abundant and permanently at attention.... Read More...
Caffeine From Four Cups of Coffee Protects the Heart With the Help of Mitochondria
A new study reports caffeine concentration, the equivalent of four cups of coffee, can promote the movement of a regulatory protein into mitochondria. This can enhance mitochondrial function and protect heart cells from damage.... Read More...
Genes Associated with Infantile Forms of Schizophrenia Identified
Researchers have identified gene mutations responsible for childhood onset schizophrenia. ... Read More...
Molecular Mechanisms of Parkinson’s Disease Unraveled
In Parkinson's disease, alpha synuclein clumps move to and damage mitochondrial proteins, making them less efficient and causing the mitochondrial to burst, leaking out chemicals that tell the cells to die, researchers say.... Read More...
Astrocytes Help the Brain Tune Breathing Rhythms
A new study reveals the role astrocytes play in regulating breathing rhythms.... Read More...
How Our Skin Communicates with the Brain
Inhibition of the P2X4 protein receptor in sensory neurons decreases sensitivity to touch, a new study reports. The findings could have implications for the development of new topical treatments for psoriasis and dermatitis.... Read More...