A new study reports an antidepressant temporarily inhibits the blood-brain barrier, allowing drugs to enter the brain. The findings could have implications for treating neurological diseases from ALS to epilepsy.
In rheumatoid arthritis, inflammation in one joint is transmitted to other joints via the sensory neuron connections in the spinal cord, leading to inflammation in the other joints. Inflammation in one joint led to an increase in ATP in other joints, which triggered an increase of a signaling molecule that resulted in inflammation. Blocking the pathway reduced the spread of inflammation.
Researchers have identified a signaling pathway that promotes sensory neuron grown and prevents peripheral neuropathy when blocked.
Recent findings from University of Warwick researchers could help find new treatments to control eating habits that lead to obesity. Researchers discovered tanycytes detect amino acids from food and directly 'tell' the brain when we feel full. Certain food, such as chicken, lentils and avocados, activate tanycytes and make us feel fuller quicker.
A new study reports caffeine concentration, the equivalent of four cups of coffee, can promote the movement of a regulatory protein into mitochondria. This can enhance mitochondrial function and protect heart cells from damage.
A new study could be the first step to developing drugs that targets carbonic anhydrase in mitochondria to help protect against aging and neurodegeneration.