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          Arc

          This shows neurons.
          FeaturedGeneticsNeurologyNeuroscience
          ·June 29, 2026·12 min read

          Arc Protein Found to Spread Toxic Tau in Alzheimer’s

          The native brain protein Arc mediates the intercellular transmission of toxic Tau via extracellular vesicles in Alzheimer's disease. While Arc helps sick neurons survive longer by expelling toxic Tau aggregates, it simultaneously promotes the spread of pathology to healthy cells, identifying the extracellular space as a prime "mid-flight" therapeutic target.
          Read More
          This shows a man walking between two DNA staircases.
          FeaturedGeneticsNeuroscience
          ·May 28, 2023·6 min read

          The DNA of Decision-Making

          A novel study uncovers a peculiar pattern of decision-making in mice, influenced by a specific gene named Arc. While searching for food, mice repeatedly visited an empty location instead of staying at a site abundant in food. However, mice lacking the Arc gene demonstrated a more practical approach, sticking with the food-rich site, thereby consuming more calories overall.
          Read More
          This is a drawing of a brain and neurons
          FeaturedNeuroscienceOpen Neuroscience ArticlesPsychology
          ·February 11, 2021·6 min read

          Tiny Population of Neurons May Have Big Role in Depression

          Induced changes in the function of AgRP neurons may contribute to depression, researchers report.
          Read More
          This shows POMC hypothalamic neurons
          FeaturedGeneticsNeuroscienceOpen Neuroscience Articles
          ·May 13, 2019·3 min read

          Obesity: The key role of a brain protein revealed – Mouse study

          The protein ACBP directly influences neurons that help both rodents and humans maintain a healthy weight.
          Read More
          A dna strand
          FeaturedGeneticsPsychology
          ·March 13, 2019·4 min read

          NIH-funded rodent study finds molecular link between adolescent alcohol use and adult anxiety

          Adolescent rats exposed to alcohol had a decrease of both Arc eRNA expression and Arc gene expression in the amygdala during adulthood. Additionally, the alcohol-exposed rats displayed increased anxiety behaviors as they aged.
          Read More
          neurons
          FeaturedGeneticsNeuroscienceOpen Neuroscience Articles
          ·June 22, 2018·5 min read

          Broken Shuttle May Interfere with Learning in Brain Disorders

          Researchers report the gamma-CaMPII protein plays a critical role in learning and memory. The shuttle protein may be dysfunctional in those with Schizophrenia and autism, hindering learning abilities, researchers report.
          Read More
          a dendrite
          FeaturedNeuroscience
          ·June 21, 2018·6 min read

          Fundamental Rule of Brain Plasticity Discovered

          Based on the actions of Arc, when one synapse strengthens, the neighboring synapses weaken, a new study reveals.
          Read More
          a brain drawing
          FeaturedGeneticsNeuroscience
          ·May 31, 2018·4 min read

          Memory Depends On Protein ‘Off Switch”

          A new study suggests a lack of cognitive flexibility and ability to retain new information may be a result of the Arc protein not being fully switched off.
          Read More
          woman running
          FeaturedNeuroscienceOpen Neuroscience Articles
          ·April 29, 2018·4 min read

          Link Between Exercise and Appetite Loss Explained

          Researchers report on the role the arcuate nucleus plays in metabolic regulation and appetite suppression following exercise.
          Read More
          brain scans
          FeaturedNeurologyNeuroscience Videos
          ·February 1, 2018·5 min read

          Stroke Recovery Improved by Sensory Deprivation

          A new study, using mouse models, demonstrates sensory deprivation can activate the brain to rewire networks following a stroke. The findings could have major implications for stroke rehabilitation in humans.
          Read More
          neurons
          FeaturedNeuroscience
          ·January 11, 2018·6 min read

          Virus Like Protein is Important for Cognition and Memory

          Researchers reveal a protein essential for memory and cognition looks and acts like a protein from a virus.
          Read More
          Image shows a cooked turkey.
          FeaturedNeuroscienceOpen Neuroscience Articles
          ·November 22, 2016·4 min read

          Scientists Find Surprising Answers to ‘Food Coma’ Conundrum

          Researchers believe they may have found a reason for that all too well known holiday phenomenon, a 'food coma'.
          Read More
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          A 3D digital illustration of a human brain side-by-side comparison, highlighting the language centers glowing brightly and equally in both a younger and older brain, while executive function areas are dimmed in the older brain.

          Aging Brains Maintain Robust Language Networks Despite Cognitive Decline

          Rejuvenation of Microglia by Youth Protein TIMP2 in the Aging Brain

          Youth Protein TIMP2 Restores Immune Function in the Aging Brain

          A multi-panel documentary photo. Left: A Black man sits alone on a locker room bench with his head down. Center: A Latino man sits withdrawn at a family kitchen table. Right: A White man looks thoughtfully at wellness pamphlets in a public waiting area. All convey isolation.

          Shame, Stigma, and Culture Prevent Male Domestic Violence Survivors From Seeking Help

          Alternative graphical abstract is shown.

          Study of Brain Immune Cells Reveals New Clues to Alzheimer’s Disease Progression

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