FeaturedNeurologyNeuroscience·October 11, 2021·3 min readWater Pill May Be Viable to Test as Alzheimer’s TreatmentBumetanide, an FDA-approved potent diuretic used to treat fluid retention caused by heart, kidney, and liver disease may lower the risk of developing Alzheimer's disease for those with a genetic predisposition.Read More
FeaturedGeneticsNeurologyOpen Neuroscience Articles·September 15, 2021·3 min readStem Cells Model Genetic Risk for Developing Alzheimer’s DiseaseStem cell study reveals astrocytes carrying the Alzheimer's associated APOE4 gene release more cholesterol than those carrying the APOE3 gene. Findings shed light on how different versions of the APOE gene in astrocytes influence amyloid-beta production and how the oversupply of cholesterol associated with APOE4 astrocytes may promote amyloid-beta formation in Alzheimer's patients.Read More
FeaturedNeurologyNeuroscience·June 25, 2021·4 min readSubconscious Changes in Movement May Predict Alzheimer’s DiseaseSubtle changes in fractal motor activity regulation in cognitively healthy women may be a sign of preclinical Alzheimer's disease, researchers report.Read More
FeaturedGeneticsNeurologyPsychology·June 17, 2021·3 min readDepression and Tau Deposits Seen in Subset of Middle-Aged PersonsDepressed middle-aged carriers of the APOEe4 Alzheimer's genetic variant are at risk of developing tau accumulations in brain areas associated with emotion and memory.Read More
FeaturedGeneticsNeurologyNeuroscienceOpen Neuroscience Articles·June 1, 2021·4 min readHealthy Lifestyle Linked to Better Cognition for Oldest Adults, Regardless of Genetic RiskAdults over 80 who maintained a healthy lifestyle, including exercise and diet, had a lower risk of cognitive decline, even if they had genetic risk factors for dementia.Read More
FeaturedNeurologyNeuroscienceVisual Neuroscience·May 14, 2021·5 min readThe Eyes Offer a Window Into Alzheimer’s DiseaseRetinal scans can help researchers detect Alzheimer's disease and track its progression in those with the APOE4 genetic risk factor for the neurodegenerative disorder. The scans can detect blood vessel deterioration linked to the genetic biomarker.Read More
FeaturedGeneticsNeurologyNeuroscience·May 6, 2021·3 min readDiscovery of Genetic Drivers Linked to Progression in Parkinson’s DiseaseResearchers identify five genetic loci linked to the progression of Parkinson's disease.Read More
FeaturedNeurologyNeuroscience·March 31, 2021·2 min readExercise May Help Slow Cognitive Decline in Some People With Parkinson’s DiseaseExercise helped to reduce cognitive decline two years later in Parkinson's patients with the APOE e4 gene variant.Read More
FeaturedGeneticsNeurologyNeuroscience·March 18, 2021·4 min readCould Leak in Blood-Brain Barrier Be Cause of Poor Memory?Researchers investigate the role the blood-brain barrier may play in age-related memory problems.Read More
FeaturedGeneticsNeurologyNeuroscience·March 3, 2021·5 min readWhy the APOE4 Gene Enhances Alzheimer’s RiskAPOE4 affects lipid metabolism, but taking choline supplements may help protect carriers from developing Alzheimer's disease and slow cognitive decline.Read More
FeaturedNeurologyNeuroscience·February 26, 2021·5 min readThe Impact of Patient Sex on Treatment Strategies for Spinal Cord InjuriesBoth the ApoE genotype and the sex of the mouse impacted the manner in which the animals with spinal cord injury responded to hypoxia treatment. Females with the ApoE e4 gene had a negative response to intermittent hypoxia.Read More
FeaturedGeneticsNeurologyNeurosciencePain·February 24, 2021·4 min readPain Perception Could Help Diagnose Alzheimer’s Before Symptoms OccurAltered pain perception could be a new biomarker to assess late-onset Alzheimer's risk in cognitively healthy individuals with the AopE4 gene before symptoms occur.Read More
