Too much or too little sleep were both linked to increased risk of cognitive decline, researchers report.
Bumetanide, an FDA-approved potent diuretic used to treat fluid retention caused by heart, kidney, and liver disease may lower the risk of developing Alzheimer's disease for those with a genetic predisposition.
Stem cell study reveals astrocytes carrying the Alzheimer's associated APOE4 gene release more cholesterol than those carrying the APOE3 gene. Findings shed light on how different versions of the APOE gene in astrocytes influence amyloid-beta production and how the oversupply of cholesterol associated with APOE4 astrocytes may promote amyloid-beta formation in Alzheimer's patients.
Subtle changes in fractal motor activity regulation in cognitively healthy women may be a sign of preclinical Alzheimer's disease, researchers report.
Depressed middle-aged carriers of the APOEe4 Alzheimer's genetic variant are at risk of developing tau accumulations in brain areas associated with emotion and memory.
Adults over 80 who maintained a healthy lifestyle, including exercise and diet, had a lower risk of cognitive decline, even if they had genetic risk factors for dementia.
Retinal scans can help researchers detect Alzheimer's disease and track its progression in those with the APOE4 genetic risk factor for the neurodegenerative disorder. The scans can detect blood vessel deterioration linked to the genetic biomarker.
Researchers identify five genetic loci linked to the progression of Parkinson's disease.
Exercise helped to reduce cognitive decline two years later in Parkinson's patients with the APOE e4 gene variant.
Researchers investigate the role the blood-brain barrier may play in age-related memory problems.
APOE4 affects lipid metabolism, but taking choline supplements may help protect carriers from developing Alzheimer's disease and slow cognitive decline.
Both the ApoE genotype and the sex of the mouse impacted the manner in which the animals with spinal cord injury responded to hypoxia treatment. Females with the ApoE e4 gene had a negative response to intermittent hypoxia.
