Unraveling Genetic Risk Factors for Alzheimer’s
Researchers say promoting conversion of glucose into brain energy could reduce risk factors and delay disease onset for those who carry Alzheimer's associated genes.... Read More...
ApoE4
Gene Variant May Increase Psychiatric Risk After TBI
A new study has linked the APOE4 gene to mental health issues some people face following TBI. Researchers report people with the APOE4 gene had significantly higher scores for depression, PTSD and anxiety following TBI than those without the genetic variant. ... Read More...
Subjective Memory May Play Role in Signaling Cognitive Decline
A new study reports listening to subjective complaints about memory lapses in people over 60 could help doctors to diagnose the onset of MCI and dementia.... Read More...
Evidence Mounts for Increased Alzheimer’s and Suicide Risks in Polluted Cities
A new study adds to growing evidence that early exposure to pollution can increase both suicide risks in younger people and Alzheimer's disease as people age.... Read More...
Researchers Fix Genetic Risk Factor of Alzheimer’s in Human Brain Cells
Researchers report they have successfully erased damage caused by Apoe4 in Alzheimer's patients by altering the gene into a harmless Apoe3-like version. ... Read More...
The Onset of Alzheimer’s:The Importance of Family History
Researchers report the closer a person gets to the age their parents started to develop Alzheimer's symptoms, the more likely they are to have amyloid plaques.... Read More...
Lifestyle Changes Prevent Cognitive Decline Even in Genetically Susceptible People
Even for those genetically susceptible to developing dementia, enhanced lifestyle counselling can help to prevent cognitive decline, a new study reports.... Read More...
Alzheimer’s Damage Reduced with Compound that Targets APOE Gene: Mouse Study
Researchers from WUSTL have identified a compound that targets APOE in mouse brains and which protects against Alzheimer's disease. The APOE4 genetic variant increases the risk of people developing Alzheimer's disease. The findings offer new possible avenues of treating the disease in humans.... Read More...
Gene Variant That Protects Against Alzheimer’s Identified
Researchers report people with a genetic predisposition to Alzheimer's and who carry a variant in the RAB10 gene, may be more resilient to the disease than those without the genetic variant.... Read More...
Middle Age Inflammation Linked to Brain Shrinkage Decades Later
According to a new study, people who have inflammation biomarkers in their blood during middle age are more likely to have increased brain shrinkage as they grow older. Researchers report the brain cell loss associated with inflammation was most prevalent in areas affected in Alzheimer's disease.... Read More...
Researchers Studying Drug’s Potential to Prevent Alzheimer’s
Researchers are testing whether low doses of Rapamycin, a drug most commonly used as an immunosuppressant following an organ transplant, can help to prevent Alzheimer's disease.... Read More...
Multi-Gene Test Predicts Alzheimer’s Better Than ApoE4 Alone
UCSF researchers have developed a new genetic risk factor test that takes into account more than 24 genetic variants, each of which are associated with a small risk of Alzheimer's disease. The researchers say the test is a better method to help identify preclinical Alzheimer's than testing for ApoE4 alone.... Read More...