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          anhedonia

          This shows the researchers
          AutismFeaturedNeurosciencePsychology
          ·January 18, 2020·4 min read

          What people who don’t like music might tell us about social interaction

          Musical anhedonia, a neurological condition where people don't enjoy music, affects 5% of the population. Researchers are exploring if this same condition could also be what impairs social bonding for some people on the autism spectrum.
          Read More
          This shows a woman playing guitar
          FeaturedNeurosciencePsychology
          ·January 18, 2020·2 min read

          Music helps researchers find link between prediction and pleasure

          Exposing subjects to music composed in an unfamiliar scale, researchers test whether reward can be derived solely from newly formed predictions.
          Read More
          This is a chemical stick and ball model of dopamine
          FeaturedNeurologyNeurosciencePsychology
          ·December 27, 2019·4 min read

          Dopamine fasting: an expert reviews the latest craze in Silicon Valley

          The latest Silicon Valley crazy of dopamine fasting promises to "reset" the brain to be more effective and appreciate the smaller things in life more easily, but does it work? Researchers look at the effect of dopamine fasting on brain health.
          Read More
          This shows a diagram from the study
          FeaturedNeurosciencePsychology
          ·December 2, 2019·3 min read

          Why stress doesn’t always cause depression

          Rats susceptible to anhedonia have more serotonin neurons in the ventral dorsal raphe nucleus. However, activating neurons in the central amygdala reduced the serotonin signaling and lowered the effects of social stress.
          Read More
          This shows brain networks
          FeaturedNeurosciencePsychology
          ·October 4, 2019·3 min read

          Promising steps towards hope for a treatment for schizophrenia

          Mu-opioid receptor (MOR) levels are significantly reduced in the striatum in those with schizophrenia. A lack of MOR system stimulation contributes to negative feelings, such as a lack of motivation and anhedonia, associated with the condition. Increasing MOR levels could help to reduce some of the symptoms of schizophrenia.
          Read More
          This shows a brain
          ElectrophysiologyFeaturedNeurologyNeurosciencePainPsychology
          ·September 26, 2019·4 min read

          Molecular link between chronic pain and depression revealed

          Inhibitory inputs to the neural circuit between the dorsolateral bed nucleus of the stria terminalis (dlBNST) to the ventral tegmental area (VTA) increase when a person is in chronic pain. This alteration is mediated by enhanced corticotropin-releasing factor signaling within the dlBNST, leading to suppression of the mesolimbic dopaminergic system. The result is depressive mood and anhedonia associated with chronic pain.
          Read More
          This shows a brain
          FeaturedNeurosciencePsychology
          ·September 5, 2019·4 min read

          Brain circuit connects feeding and mood in response to stress

          A new study identifies a novel neural network regulating feeding and mood in response to chronic stress. Inhibiting the POMC to ventral tegmental area circuit increases body weight and food intake while reducing depressive symptoms in mouse models.
          Read More
          This shows DNA
          FeaturedGeneticsNeurosciencePsychology
          ·August 8, 2019·4 min read

          Genetic variation contributes to individual differences in pleasure

          What we find pleasurable may be down to our genetics. Researchers found nucleus accumbens activation and physical anhedonia were influenced by shared genes. The experience of pleasure and physical anhedonia also appear to share some of the same genes.
          Read More
          A depressed man is shown here
          FeaturedGeneticsNeurosciencePsychology
          ·May 22, 2019·3 min read

          New therapeutic target for depression identified

          A fragment of the neuropeptide Galanin appears to play a role in anhedonia in mouse models of depression. Galanin could be a potential target for the treatment of depression.
          Read More
          This shows a depressed looking woman
          FeaturedNeurosciencePsychology
          ·May 15, 2019·3 min read

          Inflammation induces anhedonia in women but not men

          Inflammation appears to reduce reward response in females. Reduced activity in the brain's reward system is a key component of anhedonia, the loss of enjoyment in activities, a core feature of depression. The findings may explain why depression is more prevalent in women than in men.
          Read More
          a young boy sitting on a step
          FeaturedNeuroscience
          ·March 13, 2019·5 min read

          Differences in brain activity in children with anhedonia

          Using fMRI to examine the brains of children while resting, researchers discover anhedonia is associated with hyperconnectivity between the cingulo-opercular network and ventral striatum.
          Read More
          a depressed woman
          FeaturedNeuroscienceOpen Neuroscience ArticlesPsychology
          ·December 4, 2018·6 min read

          New Insights Into Loss of Pleasure in Depression

          A new study reveals a brain region that contributes to anhedonia, the loss of pleasure, in those with depression. The study also shows how ketamine acts on this brain region, explaining why the drug appears to be so effective at treating anhedonia.
          Read More
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          This shows a woman surrounded by red balls.

          Jamais Vu: When the Familiar Turns Eerily New

          This shows neurons.

          New Tools Illuminate Myelin Growth in Infants

          This shows a fly.

          From Vinyl to Visions: Fruit Flies Showcase Decision-Making Prowess

          This shows jellyfish.

          Jellyfish Show Remarkable Learning Skills

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