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          anhedonia

          Image shows a woman listening to music.
          Auditory NeuroscienceFeaturedNeuroscienceOpen Neuroscience ArticlesPsychology
          ·February 8, 2017·3 min read

          Sex, Drugs, and Rock & Roll Chemistry in the Brain

          Using a drug used to help treat addiction, researcher report exposing people to their favorite songs no longer elicit feelings of pleasure.
          Read More
          a face morphing from happy to sad
          FeaturedOpen Neuroscience ArticlesPsychology
          ·December 18, 2017·5 min read

          Could Cognitive Interventions be Useful in Treating Depression?

          Researchers report cognitive bias modification may be a useful method for treating depression.
          Read More
          This shows DNA
          FeaturedGeneticsNeurosciencePsychology
          ·August 8, 2019·4 min read

          Genetic variation contributes to individual differences in pleasure

          What we find pleasurable may be down to our genetics. Researchers found nucleus accumbens activation and physical anhedonia were influenced by shared genes. The experience of pleasure and physical anhedonia also appear to share some of the same genes.
          Read More
          a depressed girl
          FeaturedOpen Neuroscience ArticlesPsychology
          ·December 8, 2017·5 min read

          Many Different Types of Anxiety and Depression Exist

          Stanford researchers have identified five new categories of specific symptoms and brain area activation that can be applied to the diagnosis of anxiety and depression in a more specific manner.
          Read More
          This shows a head made of bubbles
          FeaturedNeurosciencePsychology
          ·November 2, 2022·3 min read

          Individuals With Schizophrenia and Social Anhedonia Show Altered Neural Processing for Social Reward Anticipation

          People with schizophrenia and social anhedonia exhibit altered neural processing for social reward processing, leading to impaired social interaction and social dysfunction.
          Read More
          This shows a depressed looking woman
          FeaturedNeurosciencePsychology
          ·May 15, 2019·3 min read

          Inflammation induces anhedonia in women but not men

          Inflammation appears to reduce reward response in females. Reduced activity in the brain's reward system is a key component of anhedonia, the loss of enjoyment in activities, a core feature of depression. The findings may explain why depression is more prevalent in women than in men.
          Read More
          This shows the outline of a head and two faces
          FeaturedNeurosciencePsychology
          ·May 11, 2022·3 min read

          Motivation/Pleasure Deficits, Not Expression Impairments, Contribute to Social Dysfunction in Schizophrenia Patients

          Amotivation and anhedonia rather than expressive dysfunction play a critical role in determining social functioning in those with schizophrenia.
          Read More
          ElectrophysiologyFeaturedPsychology
          ·July 11, 2012·7 min read

          Why the Thrill is Gone: Scientists Identify Potential Target for Treating Major Symptom of Depression

          Scientists have laid bare a novel molecular mechanism responsible for the major depression symptom, anhedonia, the loss of the ability to experience pleasure. The brain circuit involved in this newly elucidated pathway is largely identical between rodents and humans, upping the odds that the findings point toward new therapies for depression and other disorders. Additionally, opinion leaders hailed the study’s inventive methodology, saying it may offer a much sounder approach to testing new antidepressants.
          Read More
          This shows a brain
          FeaturedNeurosciencePsychology
          ·January 24, 2023·6 min read

          When Chronic Stress Activates These Neurons, Behavioral Problems Like Loss of Pleasure and Depression Result

          Anhedonia and depression arise when POMC neurons in the arcuate nucleus of the hypothalamus become hyperactive as a result of chronic stress. Reducing the activity also reduces feelings of depression and loss of pleasure.
          Read More
          This shows a man in pain
          FeaturedNeurosciencePainPsychology
          ·October 18, 2021·5 min read

          Brain Circuitry Identified That May Be Responsible for Negative Emotional Aspects of Pain

          A new rodent study uncovers a neural circuit in the brain that appears to govern pain-induced anhedonia. Altering the activity of this circuit restored motivation in pre-clinical models of pain.
          Read More
          a depressed woman
          FeaturedNeuroscienceOpen Neuroscience ArticlesPsychology
          ·December 4, 2018·6 min read

          New Insights Into Loss of Pleasure in Depression

          A new study reveals a brain region that contributes to anhedonia, the loss of pleasure, in those with depression. The study also shows how ketamine acts on this brain region, explaining why the drug appears to be so effective at treating anhedonia.
          Read More
          This shows a woman standing alone in a crowd
          FeaturedNeurosciencePsychology
          ·October 16, 2021·3 min read

          Real-Life Social Network in Schizophrenia Patients and Individuals With Social Anhedonia

          Both those with schizophrenia and those with social anhedonia have alterations in the social brain network and a diminished correlation with real-world social network size.
          Read More
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          This shows a man slumped by a wall.

          Brain Activity in PTSD: Trauma Memories Differ from Sad Ones

          This shows a brittle star.

          Brainless Brittle Stars Learn by Association

          This shows music notes and headphones.

          Music Preferences Mirror Moral Values

          This shows a man holding his ears.

          Tinnitus Linked to Auditory Nerve Loss

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