FeaturedGeneticsNeurology·February 5, 2018·4 min readThe Toxic Relationship Between ALS and Frontotemporal DementiaResearchers report the C9ORF72 genetic mutation can lead to toxicity in neurons, causing 10 percent of all ALS cases and 10 percent of FTD cases.Read More
FeaturedGeneticsNeurologyOpen Neuroscience Articles·December 20, 2017·6 min readFirst Step Toward CRISPR Cure For ALSUC Berkeley researchers report they have successfully used CRISPR-Cas9 gene editing to delay symptoms and extend lifespan in mouse models of ALS.Read More
FeaturedGeneticsNeurologyOpen Neuroscience Articles·December 8, 2017·3 min readGenetic Mutations Cause ‘Vicious Cycle’ in Most Common Form of ALSResearchers reveal a repeat element in the DNA of C9orf72 gene becomes toxic when faced with starvation, toxins and viral infection.Read More
FeaturedGeneticsNeurologyOpen Neuroscience Articles·December 1, 2017·5 min readArtificial Intelligence Finds Five New Genes Linked to ALSIBM Watson helps researchers identify five new genes associated with amyotrophic lateral sclerosis.Read More
FeaturedNeurologyNeuroscience·November 29, 2017·3 min readNeurotoxin Discovered in Lake WinnipegResearchers have discovered a neurotoxin linked to a range of neurodegenerative diseases in Lake Winnipeg. The neurotoxin, BMAA, is found in high concentration in Cyanobacteria during periods of bloom.Read More
FeaturedGeneticsNeurologyOpen Neuroscience Articles·November 13, 2017·4 min readDeadly Combination in Neurodegenerative Diseases RevealedA new mouse model has been developed that captures the pathology of sporadic neurodegenerative diseases.Read More
FeaturedNeuroscienceOpen Neuroscience Articles·November 2, 2017·3 min readSynaptic DisorderTargeting autophagy may help in the battle against ALS and other diseases that affect motor neurons, researchers report.Read More
FeaturedGeneticsNeurologyOpen Neuroscience Articles·October 17, 2017·4 min readResolving Traffic Jams in Human ALS Motor NeuronsResearchers have generated motor neurons from people with familial ALS who carry FUS mutations.Read More
FeaturedNeurologyOpen Neuroscience Articles·October 4, 2017·4 min readPathway in Neurons May Contribute to Neurodegenerative DiseasesResearchers report the injury pathway is triggered when Unc-104 is mutated. This mutation leads synapses to become defective.Read More
FeaturedNeurology·September 11, 2017·4 min readBody’s Own Defense Against ALS Actually Drives Disease Progression at Later StagesIn early stages of ALS, autophagy helps to suppress disease progression, but accelerates the spread as the disease enters into later stages, researchers report.Read More
FeaturedGeneticsNeurology·September 7, 2017·4 min readHuman Skin Cells Transformed Into Motor NeuronsWUSTL researchers have converted skin cells into motor neurons without going through the stem cell state. The new technique could help in the development of devastating neurodegenerative diseases, like ALS, that affect motor neurons.Read More
FeaturedGeneticsNeurology·August 19, 2017·6 min readFundamental ALS Pathology DiscoveredResearchers have identified a genetic mutation associated with both ALS and frontotemporal dementia.Read More
