Mortality from all causes over 40% higher in female domestic abuse survivors

Summary: Women who have experienced domestic violence are 44% more likely to die from any cause compared to the general population. They also have a 51% increased risk of developing type 2 diabetes and a 31% higher risk of being diagnosed with cardiovascular disease.

Source: University of Warwick

Women who have experienced domestic abuse appear to be more than 40 percent more likely to die from any cause compared to the general population, a study led by the Universities of Warwick and Birmingham suggests.

The researchers have also identified an increased risk of developing cardiometabolic diseases such as cardiovascular disease and type 2 diabetes in those who have experienced domestic abuse, although more research is required to determine what other factors specifically lead to an increase in their mortality.

Domestic abuse, consisting of physical, psychological, sexual, financial and emotional abuse, is thought to be an extremely common phenomenon, with an estimated 1 in 3 women globally and about 1 in 4 women in the UK having experienced it at some point in their life.

The research, which is part of a wider research agenda into the health impacts of domestic abuse, is published today (17 February) in the Journal of the American Heart Association and explores the association between exposure to domestic abuse in a female population and the subsequent development of cardiometabolic disease (cardiovascular disease, hypertension and type 2 diabetes) and all-cause mortality.

Using medical records from UK GP surgeries between 1995 and 2017, the team were able to identify 18,547 women with a recorded code relating to exposure to domestic abuse. These were matched to 72,231 like for like women (similar in terms of age, body mass index, deprivation level and smoking status) who did not have such an experience recorded.

The researchers then followed both groups whilst they were contributing to the dataset and calculated the risk of developing cardiometabolic illness and all-cause mortality. They found that the risk of developing cardiovascular disease was increased by 31% and type 2 diabetes by 51% in the exposed group. There was no association found with hypertension. They also found that all-cause mortality (i.e. due to any cause throughout the study period) among women exposed to domestic abuse was 44% higher. Although the team were not able to confirm the reason for the increased mortality, it may be partly explained by the increased cardiovascular risk. It is important to note that during the study period, the number of patients who died was relatively few (948 out of a total cohort of 91,778) likely due to the age at cohort entry being young (37 years old). The adjusted relative risk increase was 44%, with the absolute risk of death being 6 per 1,000 women per year in the exposed cohort (recorded exposure to domestic abuse) compared to 3.1 per 1,000 women per year in those without such a record in their medical notes.

However, the research published using GP records has identified a discrepancy found between the abuse reported in GP practices and the national survey data, with an estimated prevalence of 1 in 4 women in survey data who have experienced domestic abuse compared to about 0.5% coded as such in GP data. This means that many of those not coded as exposed to domestic abuse may have actually experienced some abuse. If this is the case, then it would suggest that the displayed results may be an underestimation.

This shows a woman crying
Better linkage and data sharing between public services, such as the NHS and police, could help inform GPs to further support the mental and physical health needs of their patients who have experienced domestic abuse. Image is in the public domain.

Better linkage and data sharing between public services, such as the NHS and police, could help inform GPs to further support the mental and physical health needs of their patients who have experienced domestic abuse.

Lead author Dr Joht Singh Chandan, from Warwick Medical School and the University of Birmingham’s Institute of Applied Health Research, said: “As further in-depth detail of the traumatic experiences is not available in these records it was not possible to assess whether the severity of domestic abuse was associated with a different risk impact. It is important to note that not all cases of domestic abuse go onto develop adverse health outcomes, but from this study we can see that within this dataset, the cohort of women recorded to have experienced domestic abuse are at a greater risk than those without such records present.

“Considering the prevalence of domestic abuse, there is a public health burden of cardiometabolic disease likely due to domestic abuse. Although our study was not able to answer exactly why this relationship exists, we believe that it is likely due to the effects of acute and chronic stress. Additionally, we know that exposure to domestic abuse may be associated with other lifestyle factors (such as poor diet, alcohol and smoking as seen in our study). Although we made attempts to account for the impact of this on our results, these lifestyle factors still contribute risk for the development of cardiometabolic disease, therefore need public health approaches to manage this in women who have experienced domestic abuse.

“Not every woman experiencing domestic abuse will go on to develop a long-term illness. Our understanding of the physical and mental health effects of domestic abuse is arguably still in its infancy.”

“The introduction of the recently formed violence reduction units could play a role in supporting survivors of domestic abuse, as would the Domestic Abuse Bill which would give survivors the rights and support they clearly need.”

Senior co-author Dr Krish Nirantharakumar of the University of Birmingham’s Institute of Applied Health Research, said: “It is important for us to highlight to the government and public sector bodies to not only continue funding and supporting initiatives that prevent domestic abuse, but also invest in those services which can provide the support and care for survivors who have experienced such trauma, to prevent the development of these negative consequences which can be debilitating and disabling for life. Therefore, this research clearly supports the promotion of a public health approach to abuse and violence.”

This work adds to the growing research published by the team at the two Universities exploring the physical and psychological effects of domestic abuse. In 2019, the team published research that showed that women who have experienced domestic abuse are almost twice as likely to develop fibromyalgia and chronic fatigue syndrome, while a previous study published in June 2019 showed that UK survivors of domestic abuse are three times more likely to develop severe mental illnesses.

About this neuroscience research article

Source:
University of Warwick
Media Contacts:
Peter Thorley – University of Warwick
Image Source:
The image is in the public domain.

Original Research: Open access
“The Risk of Cardiometabolic Disease and All-Cause Mortality in Female Survivors of Domestic Abuse”. Joht Singh Chandan, Tom Thomas, Caroline Bradbury‐Jones, Julie Taylor, Siddhartha Bandyopadhyay, and Krishnarajah Nirantharakumar.
Journal of the American Heart Association doi:10.1161/JAHA.119.014580.

Abstract

The Risk of Cardiometabolic Disease and All-Cause Mortality in Female Survivors of Domestic Abuse

Background
Domestic abuse (DA) against women is a global public health problem. Although the possible health burden could be substantial, the associations between DA and subsequent cardiometabolic disease (cardiovascular disease, hypertension, and type 2 diabetes mellitus) and all‐cause mortality are poorly understood.

Methods and Results
This retrospective cohort study consisted of UK‐based primary care patients between January 1, 1995, to December 1, 2017. Overall, 18 547 women exposed to DA were matched to 72 231 unexposed women by age and lifestyle factors. The main outcomes, presented as adjusted incidence rate ratios (IRRs), were the risk of developing cardiovascular disease, hypertension, type 2 diabetes mellitus, and all‐cause mortality. In total, 181 exposed women experienced a cardiovascular disease event compared with 644 of the unexposed control group, relating to an increased adjusted IRR of 1.31 (95% CI, 1.11–1.55; P=0.001). There was also an increased risk of subsequent type 2 diabetes mellitus (adjusted IRR: 1.51; 95% CI, 1.30–1.76; P<0.001) and all‐cause mortality (adjusted IRR: 1.44; 95% CI, 1.24–1.67; P<0.001) following exposure to DA. This observation was not seen with hypertension (adjusted IRR: 0.99; 95% CI, 0.88–1.12; P=0.873).

Conclusions
There is an increased risk of subsequent cardiovascular disease, type 2 diabetes mellitus, and all‐cause mortality in female survivors of DA. However, there is no association with the development of hypertension in this group, in keeping with previous literature. Considering the high prevalence of DA, clinicians should be made aware of the disproportionally increased risk and thus are encouraged to manage modifiable risk factors actively in this group.

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