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Genetics

Genetics articles related to neuroscience research will be listed here.

·May 6, 2025·6 min read

Romantic Partners Can Shape Genetic Risk for Binge Drinking

New research shows that romantic partners' habits and traits can influence how strongly genetic risk for binge drinking affects an individual. Using data from Finnish twins, scientists found that partners who smoke, show psychological distress, or exhibit low conscientiousness amplify genetic risk.

Featured Genetics Neuroscience

·May 4, 2025·5 min read

Two Key Signals Shape Brain Structure Early, Varying by Person

A new study has revealed how two morphogens, WNT and Sonic Hedgehog, act as molecular "traffic cops," directing early human brain development. Using a custom device and stem cell-derived organoids, researchers showed that exposure to these signals for just five days sets gene programs in motion that shape brain regions.

This shows the outline of a person and a brain.

Featured Genetics Neuroscience Psychology

·May 2, 2025·4 min read

Immune System Tied to Mental Health Disorders

New research reveals that immune system activity may play a causal role in conditions like schizophrenia, depression, and Alzheimer’s disease. Using Mendelian randomisation, scientists linked 29 immune-related proteins to seven neuropsychiatric disorders, suggesting the brain is not the only organ involved in mental health.

Featured Genetics Neurology Neuroscience

·April 27, 2025·4 min read

New Biomarker Enables Early, Accurate Diagnosis of Parkinson’s

Researchers have identified a biomarker in spinal fluid that can detect Parkinson’s disease in its early stages with over 90% accuracy. Using a patented immuno-infrared sensor (iRS) technology, they measured the misfolding of the alpha-synuclein (αSyn) protein, a key driver of the disease.

Auditory Neuroscience Featured Genetics Neuroscience

·April 27, 2025·4 min read

Tracing the Origins of Hearing

Researchers have developed a genetic "barcoding" method to trace how stem cells in embryos become neurons and inner ear cells. By labeling early stem cells in mice, the team followed their development and mapped the formation of the inner ear.

Featured Genetics Neuroscience

·April 26, 2025·3 min read

Umbilical Cord DNA May Predict Future Metabolic Health Risks

DNA changes in umbilical cord blood may help predict which children are at higher risk for future health issues like diabetes, liver disease, and stroke. Researchers analyzed chemical tags on DNA, known as methylation patterns, and linked specific alterations to markers of metabolic dysfunction later in childhood. Notably, changes in genes like TNS3, GNAS, and CSMD1 were tied to liver fat accumulation, high blood pressure, and abnormal waist-to-hip ratios.

Featured Genetics Neuroscience Psychology

·April 26, 2025·4 min read

Prenatal Stress Leaves Lasting Molecular Imprints on Babies

A new study reveals that stress during pregnancy can molecularly reprogram newborns' stress response systems, with significant differences between boys and girls. Researchers found that maternal stress altered entire families of tRNA fragments in umbilical cord blood, particularly those regulating acetylcholine, a key neurotransmitter.

Featured Genetics Neurology Neuroscience

·April 25, 2025·7 min read

AI Uncovers New Cause of Alzheimer’s

Researchers have discovered that a gene previously seen as a biomarker for Alzheimer’s disease, PHGDH, actually plays a causal role by disrupting gene regulation in the brain. Using AI, the team revealed that PHGDH has a hidden DNA-binding function unrelated to its known enzymatic activity. This malfunction triggers early Alzheimer’s development, offering a new target for prevention.

Brain Cancer Featured Genetics Neurology Neuroscience

·April 24, 2025·5 min read

Blood Test Tracks Brain Tumor Growth with Patient-Specific DNA Markers

Researchers have developed a personalized blood test that may offer a faster, less invasive way to track high-grade glioma progression. By identifying unique DNA junctions from each patient's tumor, the test can detect tumor DNA in the bloodstream, even before changes appear on MRI scans.

Featured Genetics Neurology Neuroscience Pain

·April 23, 2025·4 min read

Clearing Zombie Cells Eases Back Pain

A new preclinical study has found that two drugs—o-Vanillin and RG-7112—can clear “zombie cells” from spinal discs, potentially treating the root cause of chronic low back pain. These senescent cells accumulate with age or injury and cause inflammation, pain, and tissue damage.

Brain Cancer Featured Genetics Neurology Neuroscience

·April 22, 2025·6 min read

Spatial Gene Hubs Reveal Hidden Drivers of Brain Cancer

A new study reveals that the way DNA folds inside brain cells plays a critical role in glioblastoma, one of the deadliest forms of brain cancer. Researchers discovered that in cancer cells, genes cluster into 3D "hubs" that coordinate tumor-driving activity, even without mutations.

Featured Genetics Neurology Neuroscience

·April 22, 2025·5 min read

Microglia Reprogrammed to Deliver Precision Alzheimer’s Therapies

Researchers have developed engineered human microglia that detect disease-related brain changes and release therapeutic proteins precisely where needed. Using CRISPR technology, the team programmed these cells to secrete an enzyme that breaks down beta-amyloid plaques only in affected areas.