Axonal swelling in the Purkinje cells of mice had no detrimental impact on firing rate or the speed at which axons transmit signals. At peak firing rate, axons with swellings were less likely to fail than those without.
Electrophysiology
Electrophysiology research articles can cover research involving whole cell patch-clamp recordings, voltage clamping, current clamping, multielectrode arrays, EEG, brain machine interfaces, field potentials, neural prosthetics, deep brain stimulation, synaptic plasticity and other work.
Rat study reveals place cells in the hippocampus have the same patterns of activity whether they correctly, or incorrectly recall a memory. However, when the memory is incorrect, the activity begins later and is slower.
The VGLUT protein is more abundant in the dopamine neurons of female fruit flies, rodents, and humans than in males. The finding shed light on why females have greater resilience to age-related dopamine neuron loss and disorders such as Parkinson's disease.
FPP, an intermediate in the mevalonate pathway, may trigger cell death in certain situations. The findings shed new light on neurological damage caused by stroke.
People with schizophrenia and other neuropsychiatric disorders may have a more permissive blood-brain barrier which allows the immune system to become more actively involved in the central nervous system. The resulting inflammation may contribute to the clinical manifestation of psychosis-like symptoms.
Study reveals the role the mouse gene Ophn1 plays in helpless behaviors and identified three methods in which to reverse the effect.
A new map of the basal ganglia provides a blueprint of the structure of the brain region and reveals a new level of influence connected to this area.
Study identifies genes that become activated in the brain prior to the initiation of severe repetitive behaviors associated with addiction, ASD, and schizophrenia.
An increase in theta oscillations in the hippocampus help make learning and subsequent memory more efficient.
Study details a signaling pathway that prevents the overproduction of snRNPs when they are not required.
Over-expression of the synaptic protein RAPGEF2 drives synaptic loss associated with Alzheimer's disease.
Some neurons have the ability to detect and compensate for neighboring neurons, while others do not. The findings shed new light on synaptic plasticity.
