Brain CancerFeaturedNeurologyNeuroscience·December 23, 2020·4 min readAnti-Diarrhea Drug Drives Cancer Cells to Cell DeathLoperamide, an anti-diarrhea medication, induces autophagy in glioblastoma brain cancer cells.Read More
Brain CancerFeaturedGeneticsNeurologyNeuroscience·December 15, 2020·5 min readOrigin of a Deadly Brain Cancer IdentifiedResearchers have identified a cancer-causing mutation in the PDGFRA gene that drives cell mutation and growth when activated. The findings have implications for the treatment of a subset of glioblastoma brain cancer.Read More
Brain CancerFeaturedGeneticsNeurologyNeuroscience·December 8, 2020·4 min readReductive Stress in Neuroblastoma Cells Aggregates Protein and Impairs NeurogenesisReductive stress promotes protein aggregation in neuroblastoma cells and impairs neurogenesis.Read More
Brain CancerFeaturedGeneticsNeurologyNeuroscience·December 8, 2020·3 min readKey Driver of the Spread of Cancer to the Brain DiscoveredIncreased YTHDF3 expression appears to be a key driver in brain metastases.Read More
Brain CancerFeaturedNeurologyNeuroscience·October 28, 2020·4 min readCancer Cells Mediate Immune Suppression in the BrainMyeloid cells can suppress the immune response, allowing breast cancer cells to metastasize in the brain and form secondary tumor sites.Read More
Brain CancerFeaturedNeuroscience·October 14, 2020·4 min readJet Lag Conditions Impair Immune ResponseJet lag alters the microenvironment around cancerous tumor cells, making it more favorable for tumors to grow, and hinders the body's natural immune response.Read More
Brain CancerFeaturedNeurology·October 9, 2020·3 min readExperimental Glioblastoma Therapy Shows Curative PowersMP-Pt(IV), a second generation prodrug appears to have curative properties against glioblastoma when coupled with chemotherapy in mouse models.Read More
Brain CancerFeaturedNeuroscienceOpen Neuroscience Articles·October 1, 2020·4 min readMolecules Responsible for Radio-Resistant Glioblastoma IdentifiedStudy reveals how two key molecules, Rab27b, and epiregulin, interact to contribute to radioresistance in glioblastoma brain cancer.Read More
Brain CancerFeaturedGeneticsNeurology·September 10, 2020·3 min readLoss of Single Gene Fuels Deadly Childhood Brain CancerStudy describes how the loss of the SMARCB1 gene negatively impacts neural development and promotes tumor growth in ATRT, a rare and fast-progressing form of pediatric brain cancer.Read More
Brain CancerFeaturedGeneticsNeurologyOpen Neuroscience Articles·August 28, 2020·3 min readMaking Brain Cancers in Children Respond Better to TreatmentA small molecular compound has been discovered that can activate the Wnt pathway in non-Wnt subtypes of medulloblastoma brain cancer, making tumors more responsive to therapies.Read More
Brain CancerFeaturedNeurology·August 18, 2020·4 min readDrugs Against Alpha-Ketoglutarate May Combat Deadly Childhood Brain TumorExperimental drugs designed to reduce the body's natural production of alpha-ketoglutarate slow tumor growth and increase lifespan in mouse models of DIPG.Read More
Brain CancerFeaturedGeneticsOpen Neuroscience Articles·August 17, 2020·2 min readGene Targeting Helps Overcome the Resistance of Brain Cancer to TherapyMouse study reveals the deletion of the OSMR gene significantly improves glioblastoma tumor response to therapy and extended lifespan.Read More
