Brain CancerFeaturedNeurologyNeuroscience·June 15, 2019·3 min readArtificial nose identifies malignant tissue in brain tumors during surgeryResearchers have developed a new method, using diathermy smoke, to distinguish between malignant tumor tissue and healthy tissue during surgery.Read More
Brain CancerFeaturedGeneticsNeurologyNeuroscience·June 10, 2019·5 min readStudy finds macrophages’ pathway to nurture PTEN-deficient glioblastoma: Mouse studyPTEN deficiency drives an increased expression of LOX. LOX attracts macrophages which protect gliobastoma brain cancer cells and provide growth factor support for the tumor, a new mouse study reveals.Read More
Brain CancerFeaturedNeurologyNeuroscience·June 3, 2019·4 min readImmune cells determine how fast certain tumors growImmune cells can accelerate the growth of cancerous tumors in mouse models of NF1.Read More
Brain CancerFeaturedNeurologyNeuroscienceOpen Neuroscience Articles·May 30, 2019·4 min readPairing of glutamine-targeting drug and ketogenic diet fights glioblastoma in miceCombining an antibiotic drug that targets glutamine with the ketogenic diet helps kill glioblastoma cancer cells, reversing symptoms of the disease and improving survivability in mouse models.Read More
Brain CancerFeaturedNeurologyNeuroscience·May 17, 2019·4 min readNatural Compound Found in Broccoli Reawakens the Function of Potent Tumor SuppressorTargeting the gene WWP1 with indole-3-carbinol, a compound found in broccoli and other cruciferous vegetables, suppressed tumor growth in animal models of cancer.Read More
Brain CancerFeaturedGeneticsNeurologyNeuroscienceOpen Neuroscience Articles·May 16, 2019·4 min readMutations Synergize in Pediatric Brain CancerThe epigenetic histone mutation H3.1K27M works in combination with ACVR1 mutations to cause diffuse intrinsic pontine glioma tumors to form and grow quickly.Read More
Brain CancerFeaturedNeurologyNeuroscience·May 10, 2019·4 min readNew brain tumor imaging technique uses protein found in scorpion venomA synthetic, non-toxic form of scorpion venom helps illuminate brain tumors when stimulated by a near-infrared laser. A clinical trial of the agent showed it to be safe for use in brain cancer patients.Read More
Brain CancerFeaturedGeneticsNeurologyNeuroscienceOpen Neuroscience Articles·April 30, 2019·3 min readNew technique may improve detection and treatment of advanced brain cancerResearchers discovered changes in thousands of genes induced by the tumor microenvironment. The study may help in identifying new biomarkers for the early detection, and subsequent treatment, of brain cancers.Read More
Brain CancerFeaturedGeneticsNeuroscienceOpen Neuroscience Articles·April 16, 2019·4 min readScientists ‘reverse engineer’ brain cancer cells to find new targets for treatmentUsing CRISPR-Cas9 gene editing, researchers identified actionable pathways responsible for the growth of glioblastoma stem cells. By reverse engineering brain cancer cells, multiple potential new targets for cancer treatments have been uncovered.Read More
Brain CancerFeaturedGeneticsNeurologyNeuroscience·April 11, 2019·4 min readShutting down deadly pediatric brain cancer at its earliest momentsDysregulation of Zfp36l1 causes neural lineage progenitor cells to grow rapidly, taking on the properties of fast growing stem cells as they become cancerous.Read More
Brain CancerFeaturedNeurologyNeuroscience·April 6, 2019·4 min readNew hope for treating childhood brain cancerDIPG cancer cells exposed to MI-2 fail to maintain healthy levels of cholesterol and die quickly, by inhibiting lanosterol synthase. Additionally, while MI-2 destroys glioma cancer cells, the drug does not damage healthy brain cells.Read More
Brain CancerFeaturedNeurologyNeuroscience·March 31, 2019·4 min readNew glioblastoma vaccine shows promising results in phase Ib clinical trialA new vaccine for glioblastoma brain cancer suspends tumor growth and is well tolerated by patients, according to the results of an early phase clinical trial.Read More