Brain CancerFeaturedNeurologyNeuroscience·March 30, 2021·5 min readBespoke Neuroblastoma Therapy Weaponizes Cell MetabolismTwo existing medications show promise in the treatment of the deadly childhood cancer, neuroblastoma. Phenformin and AZD3965 exploit the metabolic hunger of the disease to kill cancer cells without inflicting excessive damage to healthy tissue.Read More
Brain CancerFeaturedNeurologyNeuroscienceOpen Neuroscience Articles·March 24, 2021·6 min readMutation-Specific Brain Cancer Vaccine TestedResearchers have carried out clinical trials to test a mutation-specific vaccine against malignant brain tumors. The vaccine has been found to be safe and effective in triggering the desired immune response in the brain cancer tumors.Read More
Brain CancerFeaturedNeurologyNeuroscienceOpen Neuroscience Articles·March 23, 2021·4 min readA New Strategy for Fighting Brain CancerStudy shows how cholesterol becomes dysregulated in brain cancer cells and reports the gene responsible for the dysregulation could be a potential target to help treat glioblastoma brain cancer.Read More
Brain CancerFeaturedGeneticsNeuroscience·March 8, 2021·6 min readHow Night Shift Work Increases Cancer RiskNight-shifts destroy the natural 24-hour biological rhythm in the activity of certain cancer-related genes, resulting in more vulnerability to DNA damage and causing a mistiming in the DNA repair mechanisms in shift workers.Read More
Brain CancerFeaturedNeurologyNeuroscience·February 23, 2021·3 min readTargeted Delivery of Highly Toxic Anti-Cancer Drug to Brain TumorsResearchers have developed a Dp44mT nano-carrier that can directly target glioblastoma and other brain cancer cells.Read More
Brain CancerFeaturedNeurologyNeuroscienceOpen Neuroscience Articles·February 16, 2021·3 min readCombination Treatment for Common Glioma Type Shows PromiseTreating mouse models of astrocytomas with a new combination therapy resulted in tumor regression in 60% of the mice.Read More
Brain CancerFeaturedGeneticsNeurology·February 15, 2021·5 min readNew Immunotherapy Target Discovered for Malignant Brain TumorsDisabling the CD161 pathway restores the T-cell's ability to attack gliomas and extends lifespan in animal models of brain cancer.Read More
Brain CancerFeaturedNeurology·February 12, 2021·4 min readParallels in Spread of Brain Cancer in Mammals and ZebrafishA new zebrafish model holds the potential for future studies of glioblastoma, an aggressive and lethal brain cancer.Read More
Brain CancerFeaturedGeneticsNeurology·February 11, 2021·6 min readGlioblastoma Brain Cancer Mapped in Genetic, Molecular DetailStudy reveals a detailed map of gene proteins, infiltrating cells, and signaling pathways that play significant roles in the development and progression of glioblastoma brain cancer.Read More
Brain CancerFeaturedGeneticsNeurology·February 10, 2021·3 min readBrain Tumor Study Reveals Surprising Gene Deletion and Method to Overcome Drug ResistanceInhibiting the SCD enzyme and blocking the function of FOSB blunts acquired drug resistance and improves survival in mouse models of glioblastoma brain cancer.Read More
Brain CancerFeaturedNeurology·February 5, 2021·3 min readNew Drug Targets for Childhood Cancer Neuroblastoma IdentifiedResearchers discovered all neuroblastomas arise from a single type of embryonic cell called sympathoblasts. The findings could lead to new avenues of treatment for the aggressive childhood cancer.Read More
Brain CancerFeaturedGeneticsNeurologyNeuroscience·January 15, 2021·3 min readStudy Links Cellular Transport Pathway to Aggressive Brain CancerResearchers have identified a pathway involving a protein called Rab35 in glioblastoma brain cancer. The study reports restoring the activity of Rab35 could have therapeutic benefits for those with glioblastoma.Read More
