Mapping perivascular spaces over life-span will help researchers better understand brain aging and cognitive decline.
Researchers reveal the role hundreds of miRNAs appear to play in modulating circadian rhythm.
Older adults who experienced financial exploitation showed differences in brain activity in areas associated with social judgment and decision making. Additionally, those who are exploited financially tend to be physically frailer than their peers, with particular deficits in vision and hearing.
A new computational model predicts how information deep inside the brain could flow from one network to another, and how neural network clusters can self optimize over time.
The hunger hormone ghrelin doesn't just influence where and when animals eat, it also appears to have an impact on memory. Disrupting signaling of ghrelin to the vagus nerve caused rats to forget they had just eaten, even though the animals remembered they had just had access to food. Findings suggest disrupted ghrelin signaling could negatively impact episodic memory.
Study reports modifying twelve risk factors over your lifetime could reduce dementia risk by 40%.
Humanin, a peptide encoded in mitochondria, appears to have a beneficial impact on both health and longevity in both humans and animals. Higher levels of humanin in the body are associated with longer life spans and a reduced risk of neurodegenerative disorders, like Alzheimer's disease.
Cryo-electron microscopy captures detailed snapshots of the GABAB receptor protein contorts as it interacts with GABA.
A new mathematical model examined the immune response in patients with coronavirus. The findings suggest adaptive immune response may kick in before target immune cells are depleted, slowing the infection. The interaction of the innate and adaptive immune response may explain why some with coronavirus experience a second wave infection, appearing to get better before the symptoms return and get worse. Other studies have shown those who received immunosuppressants at the start of infection had a better clinical outcome than those who did not.