Older adults who experienced financial exploitation showed differences in brain activity in areas associated with social judgment and decision making. Additionally, those who are exploited financially tend to be physically frailer than their peers, with particular deficits in vision and hearing.
A new machine-learning algorithm has uncovered new neural mechanisms and enhanced the decoding of behaviors directly from brain signaling data.
A new computational model predicts how information deep inside the brain could flow from one network to another, and how neural network clusters can self optimize over time.
The hunger hormone ghrelin doesn't just influence where and when animals eat, it also appears to have an impact on memory. Disrupting signaling of ghrelin to the vagus nerve caused rats to forget they had just eaten, even though the animals remembered they had just had access to food. Findings suggest disrupted ghrelin signaling could negatively impact episodic memory.
Study reports modifying twelve risk factors over your lifetime could reduce dementia risk by 40%.
Humanin, a peptide encoded in mitochondria, appears to have a beneficial impact on both health and longevity in both humans and animals. Higher levels of humanin in the body are associated with longer life spans and a reduced risk of neurodegenerative disorders, like Alzheimer's disease.
Cryo-electron microscopy captures detailed snapshots of the GABAB receptor protein contorts as it interacts with GABA.
A new mathematical model examined the immune response in patients with coronavirus. The findings suggest adaptive immune response may kick in before target immune cells are depleted, slowing the infection. The interaction of the innate and adaptive immune response may explain why some with coronavirus experience a second wave infection, appearing to get better before the symptoms return and get worse. Other studies have shown those who received immunosuppressants at the start of infection had a better clinical outcome than those who did not.
APOE4, a gene implicated as a risk factor for Alzheimer's disease, triggers leaks in the blood-brain barrier. The damage to capillaries APOE4 causes correlates with increased levels of cyclophilin, a protein that causes the inflammation that is a signature of early Alzheimer's.
Virologist and computational neuroscientists agree, how humans treat and trade animals may have played a significant role in the coronavirus pandemic and other viral infections.
The first round of antibody testing in L.A country reveals approximately 4.1% of the adult population has COVID-19 antibodies. Adjusting for margin of error, between 2.8% to 5.6% of the adult population has antibodies to the virus. This means between 221,000 and 442,000 adults in the Los Angeles area have been infected with coronavirus. The estimate is up to 55 times higher than confirmed cases reported for the area.