Study finds evidence of inflammation in the blood of patients during the early stages of Parkinson's disease. The findings support the theory that inflammation is a driver of the neurodegenerative disorder. The effect was most noticed in women with Parkinson's.
Dopamine receptors have different molecular features and functions depending on their anatomical location within the striatum. The findings could help develop better-targeted treatments for a range of disorders from schizophrenia to Parkinson's disease.
Researchers implanted a genetic mutation that encodes the DAT protein from a child with ASD into mice. The mice began to exhibit autism-like behavioral deficits. Mice with the DAT T356M mutation had reduced social interaction and a loss in social dominance. The mice also demonstrated an increase in hyperactivity. At the physiological level, the researchers found impaired striatal dopamine transmission and clearance.
Study reports audiovisual editing causes an increase in activity in visual processing areas, while continuous and orderly editing produces more cognitive processing activity.
Researchers report newborn granule cells in the dentate gyrus become less excitable after three weeks. The loss of excitability is crucial for the functioning of mature neurons.
A new study reports caffeine may worsen neuropsychiatric symptoms associated with Alzheimer's disease. Caffeine, researchers report, exacerbates neophobia, anxiety and cognitive flexibility in mouse models of the disease.
Researchers at UAB have developed an assessment test, that can be completed within 20 minutes, to assess the cognitive capabilities of those with Schizophrenia.
Study reports significant reduction in gray matter volume in brain regions associated with social cognition for up to two years following birth.