Blocking an overactive signaling pathway in the brains of mice within the first five weeks of their lives prevents autism symptoms from developing, researchers report.
Researchers have derived purkinje cells from patients with TSC, a genetic syndrome that includes some ASD-like symptoms. The cells, researchers say, have several characteristics that could help explain how ASD develops at the molecular level.
Researchers investigate how neurons are generated in hope to find potential new treatments for TSC and other neurological disorders.
Researchers find that, compared with neurotypical children, those with autism have multiple redundant connections between neighboring brain areas at the expense of long-distance links.