Natural resistance to capsaicin's effect in birds drove researchers to investigate a specific genetic variant that appears to be associated with pain resistance. They discovered the K710N human variant dialed down pain associated with capsaicin while enhancing the protective benefits of TRPV1. The findings could pave the way for the development of new treatments to manage pain.
Pain-sensing neurons in the put secrete substance P, a molecule that protects against gut inflammation and tissue damage by boosting specific microbes in the gut. In people with inflammatory bowel disease, the pain-sensing neurons are diminished and there are significant disruptions in pain-signaling genes.
Researchers identify genetic factors that protect from the chronification of migraines.
A new study reports your genes may determine how your heart rate and blood pressure respond to exercise.
Researchers have developed a new, minimally invasive brain stimulation technique that can induce a range of bodily movements. The technique, magneto-thermal stimulation, can be used to target highly specific brain regions and could help researchers to advance brain mapping studies.