TRPV1

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TRPV1

·February 2, 2023·6 min read

Possible New Way to Reduce Pain Inspired by Chickens

Natural resistance to capsaicin's effect in birds drove researchers to investigate a specific genetic variant that appears to be associated with pain resistance. They discovered the K710N human variant dialed down pain associated with capsaicin while enhancing the protective benefits of TRPV1. The findings could pave the way for the development of new treatments to manage pain.

Featured Neuroscience

·October 14, 2022·4 min read

Pain-Sensing Gut Neurons Protect Against Inflammation

Pain-sensing neurons in the put secrete substance P, a molecule that protects against gut inflammation and tissue damage by boosting specific microbes in the gut. In people with inflammatory bowel disease, the pain-sensing neurons are diminished and there are significant disruptions in pain-signaling genes.

This shows the back of a woman clutching her head

Featured Neurology Neuroscience Open Neuroscience Articles Pain

·February 10, 2021·4 min read

Lipid Epoxides Target Pain and Inflammatory Pathways in Neurons

Two epoxidated compounds prove to be powerful in the regulation of pain and inflammation.

Featured Genetics Neurology

·September 14, 2020·3 min read

Genetic Factors in Chronic Versus Episodic Migraine

Researchers identify genetic factors that protect from the chronification of migraines.

Featured Neuroscience Open Neuroscience Articles

·March 24, 2020·4 min read

Changing how we think about warm perception

Mouse study reveals cooling receptors in the skin are critical for the perception of warmth. The findings challenge long-standing beliefs about non-painful temperature perception.

This shows drawings of mouse heads and skin cells

Featured Neurology Neuroscience Pain

·July 26, 2019·4 min read

Skin nerves anticipate and fight infection: New type of immunity discovered

Mouse study reveals pain-sensing neurons also help fight skin infections and help prevent its spread. The findings suggest a new type of immunity.

Featured Genetics

·September 12, 2018·3 min read

Your Genes Determine How Your Heart Rate Responds to Exercise

A new study reports your genes may determine how your heart rate and blood pressure respond to exercise.

Featured Genetics Neuroscience

·August 6, 2018·2 min read

Molecular Switch Triggers Itch

Researchers have discovered two distinct pathways through which a single molecule can cause both painful and itchy skin.

Featured Neuroscience Open Neuroscience Articles

·April 29, 2018·4 min read

Link Between Exercise and Appetite Loss Explained

Researchers report on the role the arcuate nucleus plays in metabolic regulation and appetite suppression following exercise.

Featured Neuroscience

·October 11, 2017·5 min read

Fever in Early Pregnancy Linked to Birth Defects

Fever suffered during the first trimester of pregnancy can lead to facial deformities and heart defects in the fetus, a new study reveals.

Featured Neurology Neuroscience

·August 16, 2017·5 min read

Scientists Use Magnetic Fields to Remotely Stimulate Brain and Control Body Movements

Researchers have developed a new, minimally invasive brain stimulation technique that can induce a range of bodily movements. The technique, magneto-thermal stimulation, can be used to target highly specific brain regions and could help researchers to advance brain mapping studies.