SSRI's, ketamine, and tricyclic antidepressants all bind with TrkB. The findings challenge the roles serotonin and glutamate receptors play in the effects of antidepressant medications.
Study examines the interactions between stem cells and neurons in both tissue regeneration and the development of cancerous tumors.
Researchers report a signalling mechanism in the brain shapes social behavior. The findings may have implications for better understanding social hierarchies, aggression and bullying.
Researchers successfully used a synthetic compound to stimulate a receptor pathway to promote remyelination in the brain. The technique may have significant beneficial implications for treating multiple sclerosis, researchers say.
A new study reveals psychedelics increase dendrites, dendritic spines and synapses, while ketamine may promote neuroplasticity. The findings could help develop new treatments for anxiety, depression and other related disorders.
Researchers have developed a new method that appears to successfully help treat neuropathic pain in animal models.
Researchers have identified a molecular mechanism that contributes to a slowed maturation of fast spiking neurons. The developmental delay has been implicated in Fragile X. However, researchers were able to restore normal maturation speed by administering an activator of the TrkB protein.
A plasma membrane protein affects the generation of new neurons in the adult hippocampus, a new study reports.
Researchers have identified a novel signaling system that controls neuroplasticity.
A new study sheds light on the unexpected molecular mechanisms in place for memories to form.
Researchers discover elevated levels of TG2 in the prefrontal cortex of people who committed suicide.
Findings could have implications for the development of new treatment strategies for schizophrenia and other neuropsychiatric disorders.
