Thrombospondin-2, a protein with cell adhesion properties usually secreted by astrocytes, prompted a strong increase in synapses in male-derived neurons but showed no effect in females.
Study sheds new light on the role noncoded RNAs play at the synapse.
Findings shed new light on how the brain wires during development.
A new theory of memory visualizes the brain as an organic super-computer that runs complex binary code with neurons acting like mechanical computers. The theory is based on the discovery of the protein molecule, talin, which contains switch-like domains that change shape in response to pressure in mechanical force by a cell.
Prolonged anesthesia significantly alters the synaptic architecture of the brain, regardless of age.
Gray matter damage associated with multiple sclerosis progression may be caused by inflammatory reactions that lead to synaptic loss.
Using a snap-freezing method, researchers have been able to reveal the true structure of the connections that join neurons together in the adult brain.
Researchers have developed a novel approach to measure the activity and strength of individual synapses that drive a neuron's response to sensory input.
Astrocytes are involved in regulating inhibitory synapses by binding to neurons through the NrCAM adhesion molecule.