synapses

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synapses

This shows neurons in the developing brain

Featured Neuroscience Neuroscience Videos Open Neuroscience Articles

·July 22, 2020·5 min read

New Role for White Blood Cells in the Developing Brain

When T helper cells are absent in the brain, microglia remain suspended between the fetal and adult developmental state. Mice lacking brain T cells showed changes in behavior and defective synaptic pruning. The study reveals the critical role T cells play in the development of the brain. Read More

Featured Genetics Neurology Open Neuroscience Articles

·July 18, 2020·5 min read

Study Reveals Intricate Details About Huntington’s Disease Protein

A mutated form of the huntingtin protein disrupts the normal movement of vesicles holding HT and Rab4. This leads to defects in synapses, resulting in movement abnormalities and lifespan decreases in fruit fly larvae. Findings suggest Rab4 could be a novel therapeutic target for the early intervention of Huntington's disease, before the neuronal loss and behavioral deficits associated with the neurodegenerative disorder. Read More

This shows a brain made up of network nodes

Featured Genetics Neurology Neuroscience Psychology

·July 17, 2020·4 min read

Synapse-Saving Proteins Discovered, Opening Possibilities in Alzheimer’s and Schizophrenia

Study identified a new class of proteins that protect synapses from being destroyed. The findings have important implications for both Alzheimer's disease and schizophrenia. Read More

Featured Neuroscience Open Neuroscience Articles

·July 6, 2020·6 min read

To Let Neurons Talk, Immune Cells Clear Paths Through Brain’s ‘Scaffolding’

Dropping the level of the IL-33 immune molecule increased the number of synapses in the brain. In older mice, ramping up IL-33 helped push the number of new synapses toward a more youthful state. Read More

Featured Neuroscience

·June 18, 2020·4 min read

How chandelier cells light up the brain

Chandelier cells have an unusual direct method of communication. Unlike other neurons, chandelier cells connect directly to the part of a target neuron that initiates a spike. Read More

Featured Neuroscience Psychology

·May 18, 2020·2 min read

How experiencing traumatic stress leads to aggression

Strengthened amygdala pathways increase aggression in those who have experienced trauma. The findings could lead to new treatments for PTSD. Read More

Featured Neuroscience

·May 4, 2020·2 min read

How synaptic changes translate to behavior changes

Learning produces changes in connectivity via multiple synaptic mechanisms that are consistent with observed behavioral changes. Read More

Featured Genetics Neurology Neuroscience

·May 1, 2020·4 min read

Molecular basis of rare neurological disorder reveals potential treatment

Study reveals how mutations of the synaptotagmin-1 protein can lead to a rare disorder called syt1-associated neurodevelopmental disorder. Mutations of the SYT1 gene interfere with neurotransmitter release, and the altered protein becomes less responsive to calcium. Read More

Featured Neuroscience Open Neuroscience Articles

·April 16, 2020·2 min read

Insight into the synapses

The direct contact of mGluR4 receptors with other key proteins plays a significant role in the regulation of synaptic activity. Read More

Autism Featured Genetics Neuroscience Open Neuroscience Articles

·April 15, 2020·5 min read

Autism in males linked to defect in brain immune cells and microglia

An over-production of eIF4E impairs microglial cells, hampering their ability to effectively prune synapses and leading to autism-like behaviors in male mouse models of ASD. Read More

Featured Neurology Neuroscience Psychology

·April 2, 2020·5 min read

How T. gondii infection causes seizures, and psychiatric illness for some

Study shows how Toxoplasma parasitic infections promote the loss of inhibitory signaling in the brain by altering the behavior of microglia. Read More

This shows blood vessels under the 2 photo microscope

Featured Neuroscience Neuroscience Videos

·March 21, 2020·7 min read

High-speed microscope captures fleeting brain signals

Combining two-photon fluorescent microscopy and all-optical laser scanning, researchers can image the brain of an alert mouse 1,000 times a second, recording the passage of millisecond electrical pulses through neurons. Read More

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