Gray matter damage associated with multiple sclerosis progression may be caused by inflammatory reactions that lead to synaptic loss.
Using a snap-freezing method, researchers have been able to reveal the true structure of the connections that join neurons together in the adult brain.
Researchers have developed a novel approach to measure the activity and strength of individual synapses that drive a neuron's response to sensory input.
Astrocytes are involved in regulating inhibitory synapses by binding to neurons through the NrCAM adhesion molecule.
Low-level exposure to lead during development does not lead to alcohol use disorder, but does alter the neural circuits in a way that if addiction occurs, it makes it harder to refrain from returning to addiction related behaviors.
A clusterization approach allows researchers to analyze dendritic spines in new ways.
The retrieval of mitochondria via a feedback loop is vital to sustaining synaptic transmission.
A newly designed synthetic compound could act as a prototype for a novel class of drugs to treat neurological damage.
When T helper cells are absent in the brain, microglia remain suspended between the fetal and adult developmental state. Mice lacking brain T cells showed changes in behavior and defective synaptic pruning. The study reveals the critical role T cells play in the development of the brain.