Strengthened amygdala pathways increase aggression in those who have experienced trauma. The findings could lead to new treatments for PTSD.
Learning produces changes in connectivity via multiple synaptic mechanisms that are consistent with observed behavioral changes.
Study reveals how mutations of the synaptotagmin-1 protein can lead to a rare disorder called syt1-associated neurodevelopmental disorder. Mutations of the SYT1 gene interfere with neurotransmitter release, and the altered protein becomes less responsive to calcium.
An over-production of eIF4E impairs microglial cells, hampering their ability to effectively prune synapses and leading to autism-like behaviors in male mouse models of ASD.
Combining two-photon fluorescent microscopy and all-optical laser scanning, researchers can image the brain of an alert mouse 1,000 times a second, recording the passage of millisecond electrical pulses through neurons.
Enhancing mitochondrial transportation and cellular energetics could help promote regeneration and function following spinal cord injury.
A single neuron, through its axon, is capable of simultaneously producing different effects in separate areas of the cerebral cortex.
Study reports repeats in genes associated with Fragile X syndrome normally regulate how and when proteins are made in neurons.