Researchers have created a new blueprint that outlines how embryonic stem cells from mice become sensory interneurons and identified a method for producing sensory interneurons in a lab setting. If the results can be replicated in human stem cells, researchers say the findings could contribute to the development of therapies to restore sensation to those suffering nerve damage and spinal cord injury.
A brain-penetrating experimental drug in development as a cancer treatment can foster the regeneration of damaged nerves following spinal cord injury, researchers report.
A new injectable therapy that uses specially engineered molecules could help treat spinal cord injury.
Gene therapy that inhibits targeted nerve cell signals effectively improves symptoms of neuropathic pain without negative side effects in mouse models of spinal cord injury or peripheral nerve damage.
An innovative new system that includes electronic implants directly onto the spinal cord reactivates neurons that control blood pressure, allowing a patient with multiple system atrophy-parkinsonian type (MSA-P) to retain consciousness when she is in an upright position.
Researchers engineered functional human spinal cord tissue from cells and human materials which, when implanted into animal models of spinal cord injury, restored walking ability in 80% of the test subjects.
Harnessing the power of "dancing molecules", researchers have developed a new injectable therapy that repairs tissue damage and reverses paralysis in mouse models. Within four weeks of receiving the injection, paralyzed mice regained the ability to walk.
Fenofibrate, an FDA-approved drug commonly used to treat high cholesterol, activated support cells around sensory neurons in mouse models of spinal cord injury, helping them regrow twice as fast as a placebo.