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SLE

·October 8, 2019·4 min read

Stem cell transplant reverses disabling MS-like disease

Hematopoietic stem cell transplantation reversed neuromyelitis optica. Five years following transplantation, only 2 of twelve patients had relapsed.

Featured Neurology Neuroscience Open Neuroscience Articles

·August 7, 2019·4 min read

Blood clotting proteins in urine discovered as biomarkers of lupus nephritis

Clotting proteins are elevated in the urine of patients with lupus nephritis. The findings provide a new biomarker for the autoimmune disease.

This diagram shows how lupus affects the body

Featured Genetics Neuroscience

·July 2, 2019·3 min read

B cells off the rails early in lupus

A key finding in the origins of lupus has been discovered. In those with systemic lupus erythematosus, B cells are abnormally activated. This results in the production of antibodies which react against the patient's own tissue, causing a range of symptoms including rashes, joint pain, and fatigue.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·May 17, 2019·3 min read

Groundbreaking genetic discovery shows why Lupus develops

Rare gene variants BLK and BANK1 are present in a substantial percentage of people with Lupus. The genetic variants suppress 1RF5 and type-1 1Fn in B cells, causing dysfunction in the immune cells.

This shows VGLL3 expression in different skin samples

Featured Neurology Neuroscience Open Neuroscience Articles

·April 19, 2019·5 min read

Skin discovery may help explain why women get autoimmune diseases far more often than men

Skin cells may hold the key to explaining why women are more prone to developing autoimmune diseases, such as lupus than men. Researchers found women have more VGLL3 in their skin cells than men. VGLL3 pushes the immune system into overdrive, resulting in the 'self-attacking' autoimmune response, the mouse study revealed. Findings strongly implicate VGLL3 as a pivotal catalyst in sex-based autoimmunity.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·April 5, 2019·6 min read

Unlocking the female bias in lupus

Disruptions in maintaining X chromosome inactivation of T cells may explain why women are more prone to developing SLE than males.

Featured Genetics Neurology

·December 18, 2018·3 min read

A Single Faulty Gene Can Lead to Lupus

Researchers report defects in the Ets1 gene is linked to characteristics associated with systemic lupus erythematosus immune abnormalities.

Featured Neurology

·October 2, 2017·5 min read

Preventing Autoimmune Disease After Viral Infections

A study in Nature Immunology reports on the mechanism that helps to prevent autoimmune diseases from developing following infection. Researchers report a population of immune cells develop during late stages of the immune response to influenza infection.

Featured Genetics Neurology Open Neuroscience Articles

·September 4, 2017·6 min read

Probing What Fuels “Runaway Train” of Autoimmune Diseases

According to researchers, rogue B cells can trigger an override that may be responsible for autoimmune attacks and diseases.

Featured Genetics Neurology Open Neuroscience Articles

·August 4, 2017·6 min read

Genetic Risk for Lupus Tied to Ancestry

Researchers have identified 24 new genes associated with lupus.

Featured Neuroscience Psychology

·June 15, 2017·5 min read

Surprising New Link Between Inflammation and Mental Illness

A new study considers whether immune system changes in people with lupus contribute to neuropsychiatric symptoms associated with the disease.

Featured Genetics Neurology Open Neuroscience Articles

·May 10, 2017·3 min read

Trigger For Autoimmune Disease Identified

Researchers have discovered a possible trigger for autoimmune diseases such as lupus, Crohn's disease and MS. Findings may explain how women are more susceptible to autoimmune disorders than men.

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SLE

Stem cell transplant reverses disabling MS-like disease

Blood clotting proteins in urine discovered as biomarkers of lupus nephritis

B cells off the rails early in lupus

Groundbreaking genetic discovery shows why Lupus develops

Skin discovery may help explain why women get autoimmune diseases far more often than men

Unlocking the female bias in lupus

A Single Faulty Gene Can Lead to Lupus

Preventing Autoimmune Disease After Viral Infections

Probing What Fuels “Runaway Train” of Autoimmune Diseases

Genetic Risk for Lupus Tied to Ancestry

Surprising New Link Between Inflammation and Mental Illness

Trigger For Autoimmune Disease Identified

Engineered Protein Reveals Hidden Incoming Signals Between Neurons

Numbers in Vision Can Shift How We Perceive Space

Study Finds Way to Reverse Alzheimer’s

Working Nights May Increase Cancer Risk

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