Working memory isn't confined to one area of the brain. It requires synchronous activity of at least two brain areas.
Activity of the c-Fos gene begins the increase on the ninth day of exposure to antidepressants. By day 14, mice showed behavioral changes associated with SSRI use. This may explain why suicide rates drop after nine days of treatment, and symptoms of depression improve after three weeks.
Sensory neurons that send signals from the intestines to the brain stem extend to the interface of areas of the intestine that are exposed to high levels of microbial compounds. Turning off the neurons, researchers observed activated neurons in the brainstem as well as activation of gut neurons that control intestinal motility. The findings shed light on the potential mechanisms behind neurological abnormalities and intestinal diseases, including IBS.
Normally bushy networks of neural fibers within fat tissue shrink in the absence of leptin, but grow back when the hormone is administered in drug form. The alterations influence the ability to burn energy stored in fat in mouse models.
Researchers are sifting through millions of antibodies produced by those who have recovered from COVID-19 to find which ones neutralize the virus. The team has already identified several antibodies that block coronavirus from interacting with its receptors.
A new zebrafish study reveals the important role the cerebellum plays in cognition, decision making, and motor planning.
Infections in the intestine may contribute to irritable bowel syndrome (IBS) by damaging the gut's nervous system. Researchers explore why neurons in the gut die as a result of infection and how the immune system normally protects them. The findings could provide new avenues of treatment for IBS.
The posterior inferotemporal cortex plays a critical role in attention. Researchers say the discovery may require rethinking old concepts of attentional control.
Study illuminates the role of non-coding mutations in autism spectrum disorder. Researchers say non-coding mutations may also shed light on an array of other neurological and health disorders.
Researchers have developed small molecules that inhibit one of the main enzymes implicated in autoimmune response. The research could lead to potential new medications for a range of autoimmune diseases.
A new microscopy technique integrates existing and novel approaches to build a clearer picture of the workings of neurons in the brain. The technique captures cellular activity across large tissue volumes in greater detail than previous techniques have allowed for.
DIPG cancer cells exposed to MI-2 fail to maintain healthy levels of cholesterol and die quickly, by inhibiting lanosterol synthase. Additionally, while MI-2 destroys glioma cancer cells, the drug does not damage healthy brain cells.
