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          Progressive Supranuclear Palsy

          This shows a brain.
          FeaturedNeurologyNeuroscience
          ·April 30, 2025·5 min read

          Skin Test Detects Neurodegenerative Disease PSP with High Accuracy

          Researchers have developed a skin-based test that can detect misfolded tau proteins specific to progressive supranuclear palsy (PSP), offering a faster, more accurate diagnosis than current methods. This breakthrough could improve patient assignment to clinical trials and eventually guide targeted, precision treatments.
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          This shows a woman's head.
          FeaturedNeurologyNeuroscience
          ·September 4, 2024·4 min read

          Drug Trial Offers Hope for Progressive Supranuclear Palsy

          A new clinical trial will test three drugs concurrently to find treatments for progressive supranuclear palsy (PSP), a rare and fatal neurodegenerative disorder. The trial aims to slow the relentless progression of PSP, which currently has no cure.
          Read More
          This shows brain scans.
          FeaturedNeurologyNeuroscience
          ·July 5, 2024·6 min read

          Breakthrough in Diagnosing Deadly Brain Disorder PSP

          Researchers identified protein biomarkers in spinal fluid that can diagnose progressive supranuclear palsy (PSP) in living patients. Using high-throughput technology, they found a distinct protein pattern in PSP patients, offering hope for early diagnosis and targeted treatments.
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          This shows neurons and a head.
          FeaturedGeneticsNeurologyNeuroscience
          ·November 3, 2023·5 min read

          Promising Targets Discovered for Rare Brain Disorder PSP

          Researchers have identified new therapeutic targets for progressive supranuclear palsy (PSP), an incurable brain disorder with symptoms mimicking Parkinson's and dementia. The study focused on RNA sequencing from brain samples of over 400 individuals.
          Read More
          This shows a brain
          FeaturedNeurologyNeuroscience
          ·January 6, 2023·4 min read

          Inflammatory Trigger a New Clue in Alzheimer’s and PSP

          An inflammatory trigger like one present during viral infections is elevated in those with Alzheimer's disease and progressive supranuclear palsy (PSP).
          Read More
          This shows the outline of a head
          FeaturedNeurologyNeuroscience
          ·October 13, 2022·5 min read

          Memory and Logic Test Detects Dementia Signs up to Nine Years Ahead of Diagnosis

          People who later developed Alzheimer's disease scored poorly on memory and logic-based tests, as well as reaction times and grip tests. They were also more likely to have experienced a fall within the past 12 months. Those who developed PSP were twice as likely to experience a fall.
          Read More
          This shows a brain
          FeaturedGeneticsNeurologyNeuroscience
          ·August 18, 2022·6 min read

          New Dementia Risk Genes Identified Through Novel Testing Approach

          Researchers have identified multiple new risk genes for Alzheimer's disease and progressive supranuclear palsy (PSP).
          Read More
          This shows a brain
          FeaturedNeurologyNeuroscience
          ·April 4, 2022·7 min read

          Loss of Neurons, Not Lack of Sleep, Makes Alzheimer’s Patients Drowsy

          Degeneration of neurons associated with wakefulness, and not a lack of sleep, makes Alzheimer's patients more drowsy. The degeneration of these neurons is caused by the tau protein. In PSP, the damage to the neurons was associated with symptoms of sleep deprivation.
          Read More
          This shows astrocytes
          FeaturedNeurologyNeuroscienceOpen Neuroscience Articles
          ·March 19, 2022·5 min read

          New Strategy Reduces Brain Damage in PSP, Alzheimer’s, and Related Disorders in Mice

          Alpha2-NKA, a protein that drives toxicity in astrocytes, was discovered in higher levels of brain samples from people who died of PSP, Alzheimer's and other tau-related neurodegenerative disorders. Treatment with an FDA-approved drug called digoxin may suppress the inflamed astrocytes and halt disease progression for those with tauopathy disorders.
          Read More
          This shows a brain
          FeaturedGeneticsNeurologyNeuroscience
          ·May 19, 2021·6 min read

          New Insight Into Protein Production in Brain Could Help Tackle Dementia

          Researchers have identified a layer of genetic material involved in controlling the production of tau in the brain. The material is part of a larger family of non-coding genes that regulate and control other brain proteins associated with neurodegenerative disorders, such as Alzheimer's disease, Parkinson's, and PSP. The findings could lead to the development of new therapeutics to treat a range of neurodegenerative disorders.
          Read More
          This shows a brain scan from the study
          FeaturedGeneticsNeurologyNeuroscienceOpen Neuroscience Articles
          ·January 5, 2020·5 min read

          Up to 10,000 people could be living with rare neurological disorders

          Progressive supranuclear palsy (PSP) and corticobasal syndrome (CBS), two atypical parkinsonian syndromes, may be twice as common as previously believed, researchers report.
          Read More
          This shows an old woman sleeping
          FeaturedNeurologyNeuroscience
          ·August 12, 2019·5 min read

          Alzheimer’s disease destroys neurons that keep us awake

          Tau accumulations disrupt wake-promoting neurons. The findings help explain why day-time napping and sleep disruptions are often reported in Alzheimer's patients.
          Read More
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          This shows an ear.

          Gene Therapy Restores Hearing in Those with Deafness

          This shows a brain.

          Forever Chemicals May Disrupt Brain Development

          This shows kids playing games.

          Kids Outsmart AI in Puzzle Game That Builds Critical Thinking

          This shows a neuron.

          Drug-Coated Neural Implants Reduce Immune Rejection

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