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          Progressive Supranuclear Palsy

          This shows neurons and a head.
          FeaturedGeneticsNeurologyNeuroscience
          ·November 3, 2023·5 min read

          Promising Targets Discovered for Rare Brain Disorder PSP

          Researchers have identified new therapeutic targets for progressive supranuclear palsy (PSP), an incurable brain disorder with symptoms mimicking Parkinson's and dementia. The study focused on RNA sequencing from brain samples of over 400 individuals.
          Read More
          This shows a brain
          FeaturedNeurologyNeuroscience
          ·January 6, 2023·4 min read

          Inflammatory Trigger a New Clue in Alzheimer’s and PSP

          An inflammatory trigger like one present during viral infections is elevated in those with Alzheimer's disease and progressive supranuclear palsy (PSP).
          Read More
          This shows the outline of a head
          FeaturedNeurologyNeuroscience
          ·October 13, 2022·5 min read

          Memory and Logic Test Detects Dementia Signs up to Nine Years Ahead of Diagnosis

          People who later developed Alzheimer's disease scored poorly on memory and logic-based tests, as well as reaction times and grip tests. They were also more likely to have experienced a fall within the past 12 months. Those who developed PSP were twice as likely to experience a fall.
          Read More
          This shows a brain
          FeaturedGeneticsNeurologyNeuroscience
          ·August 18, 2022·6 min read

          New Dementia Risk Genes Identified Through Novel Testing Approach

          Researchers have identified multiple new risk genes for Alzheimer's disease and progressive supranuclear palsy (PSP).
          Read More
          This shows a brain
          FeaturedNeurologyNeuroscience
          ·April 4, 2022·7 min read

          Loss of Neurons, Not Lack of Sleep, Makes Alzheimer’s Patients Drowsy

          Degeneration of neurons associated with wakefulness, and not a lack of sleep, makes Alzheimer's patients more drowsy. The degeneration of these neurons is caused by the tau protein. In PSP, the damage to the neurons was associated with symptoms of sleep deprivation.
          Read More
          This shows astrocytes
          FeaturedNeurologyNeuroscienceOpen Neuroscience Articles
          ·March 19, 2022·5 min read

          New Strategy Reduces Brain Damage in PSP, Alzheimer’s, and Related Disorders in Mice

          Alpha2-NKA, a protein that drives toxicity in astrocytes, was discovered in higher levels of brain samples from people who died of PSP, Alzheimer's and other tau-related neurodegenerative disorders. Treatment with an FDA-approved drug called digoxin may suppress the inflamed astrocytes and halt disease progression for those with tauopathy disorders.
          Read More
          This shows a brain
          FeaturedGeneticsNeurologyNeuroscience
          ·May 19, 2021·6 min read

          New Insight Into Protein Production in Brain Could Help Tackle Dementia

          Researchers have identified a layer of genetic material involved in controlling the production of tau in the brain. The material is part of a larger family of non-coding genes that regulate and control other brain proteins associated with neurodegenerative disorders, such as Alzheimer's disease, Parkinson's, and PSP. The findings could lead to the development of new therapeutics to treat a range of neurodegenerative disorders.
          Read More
          This shows a brain scan from the study
          FeaturedGeneticsNeurologyNeuroscienceOpen Neuroscience Articles
          ·January 5, 2020·5 min read

          Up to 10,000 people could be living with rare neurological disorders

          Progressive supranuclear palsy (PSP) and corticobasal syndrome (CBS), two atypical parkinsonian syndromes, may be twice as common as previously believed, researchers report.
          Read More
          This shows an old woman sleeping
          FeaturedNeurologyNeuroscience
          ·August 12, 2019·5 min read

          Alzheimer’s disease destroys neurons that keep us awake

          Tau accumulations disrupt wake-promoting neurons. The findings help explain why day-time napping and sleep disruptions are often reported in Alzheimer's patients.
          Read More
          a brain
          FeaturedNeurology
          ·January 5, 2018·4 min read

          How Alzheimer’s Spreads Through the Brain

          Researchers investigate how toxic proteins associated with Alzheimer's disease spread throughout the brain.
          Read More
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          NeurologyNeuroscienceNeuroscience Business
          ·November 4, 2017·7 min read

          Cortice Biosciences Announces Presentation of Results from Placebo-Controlled Phase 1 Clinical Trials Evaluating TPI 287 for Treatment of Alzheimer’s Disease and Related Tauopathies

          Cortice Biosciences announced today results from placebo-controlled, double-blinded Phase 1 studies evaluating TPI 287, a brain penetrable microtubule stabilizing agent, for the treatment of Alzheimer’s disease, progressive supranuclear palsy (PSP) and corticobasal syndrome (CBS).
          Read More
          Image shows brain scans.
          FeaturedNeurology
          ·August 15, 2016·5 min read

          How Parkinson’s Alters Brain Activity Over Time

          Researchers have identified how specific brain areas change over time in patients with Parkinson's disease.
          Read More
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          This shows a woman and a robot.

          AI’s Vulnerability to Misguided Human Arguments

          This shows a mom and child.

          Maternal Inflammation Linked to Child Behavioral Dysregulation

          This shows a brain.

          Brain Area Associated With Impulse Control Discovered

          This shows an older lady.

          Serotonin Drop Linked to Memory Decline in Early Alzheimer’s Progression

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