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Progressive Supranuclear Palsy

·August 12, 2019·5 min read

Alzheimer’s disease destroys neurons that keep us awake

Tau accumulations disrupt wake-promoting neurons. The findings help explain why day-time napping and sleep disruptions are often reported in Alzheimer's patients.

Featured Neurology Neuroscience

·July 5, 2024·6 min read

Breakthrough in Diagnosing Deadly Brain Disorder PSP

Researchers identified protein biomarkers in spinal fluid that can diagnose progressive supranuclear palsy (PSP) in living patients. Using high-throughput technology, they found a distinct protein pattern in PSP patients, offering hope for early diagnosis and targeted treatments.

Neurology Neuroscience Neuroscience Business

·November 4, 2017·7 min read

Cortice Biosciences Announces Presentation of Results from Placebo-Controlled Phase 1 Clinical Trials Evaluating TPI 287 for Treatment of Alzheimer’s Disease and Related Tauopathies

Cortice Biosciences announced today results from placebo-controlled, double-blinded Phase 1 studies evaluating TPI 287, a brain penetrable microtubule stabilizing agent, for the treatment of Alzheimer’s disease, progressive supranuclear palsy (PSP) and corticobasal syndrome (CBS).

Featured Neurology Neuroscience Psychology

·March 24, 2026·9 min read

Depression and Gut Issues Linked to Future PSP

A new study identified five key risk factors for Progressive Supranuclear Palsy (PSP), including depression 10 years pre-diagnosis. The findings suggest the disease develops silently for a decade before motor symptoms appear.

Featured Neurology Neuroscience

·September 4, 2024·4 min read

Drug Trial Offers Hope for Progressive Supranuclear Palsy

A new clinical trial will test three drugs concurrently to find treatments for progressive supranuclear palsy (PSP), a rare and fatal neurodegenerative disorder. The trial aims to slow the relentless progression of PSP, which currently has no cure.

Featured Neurology

·January 5, 2018·4 min read

How Alzheimer’s Spreads Through the Brain

Researchers investigate how toxic proteins associated with Alzheimer's disease spread throughout the brain.

Featured Neurology

·August 15, 2016·5 min read

How Parkinson’s Alters Brain Activity Over Time

Researchers have identified how specific brain areas change over time in patients with Parkinson's disease.

Featured Neurology

·September 2, 2015·4 min read

How Tau Accumulates and Caused Neurodegenerative Disorders

A new study reports appoptosin initiates a path that leads to tau accumulation in neurodegenerative disorders.

Featured Neurology Neuroscience

·January 6, 2023·4 min read

Inflammatory Trigger a New Clue in Alzheimer’s and PSP

An inflammatory trigger like one present during viral infections is elevated in those with Alzheimer's disease and progressive supranuclear palsy (PSP).

Featured Neurology Neuroscience

·April 4, 2022·7 min read

Loss of Neurons, Not Lack of Sleep, Makes Alzheimer’s Patients Drowsy

Degeneration of neurons associated with wakefulness, and not a lack of sleep, makes Alzheimer's patients more drowsy. The degeneration of these neurons is caused by the tau protein. In PSP, the damage to the neurons was associated with symptoms of sleep deprivation.

Featured Neurology Neuroscience

·October 13, 2022·5 min read

Memory and Logic Test Detects Dementia Signs up to Nine Years Ahead of Diagnosis

People who later developed Alzheimer's disease scored poorly on memory and logic-based tests, as well as reaction times and grip tests. They were also more likely to have experienced a fall within the past 12 months. Those who developed PSP were twice as likely to experience a fall.