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Featured Genetics Neurology Neuroscience

·August 30, 2019·4 min read

Creation of new brain cells plays an underappreciated role in Alzheimer’s disease

Microglia may play a significant role in disrupting neurogenesis in those with Alzheimer's disease. When mice were given drugs which caused microglial cells to die, neurogenesis returned to normal.

This image shows stained slices from the study.

Featured Neurology Open Neuroscience Articles

·April 29, 2015·5 min read

Amyloid Beta Production Blocked in Mouse Model of Alzheimer’s

Findings promising as a potential early therapeutic intervention for AD.

This image shows two sections of cortex, one froma a control mouse and the other from a mouse with the presenilin-1 mutation.

Featured Genetics Neurology

·March 11, 2015·3 min read

How Genetic Changes Lead to Familial Alzheimer’s Disease

New findings could help provide a novel approach for developing treatments for familial Alzheimer's disease.

This image shows amyloid plaques associated with alzheimer disease from an HE stained brain slice.

Featured Neurology

·October 13, 2014·4 min read

Novel Culture System Replicates Course of Alzheimer’s Disease and Confirms Amyloid Hypothesis

Using an innovative culture system, researchers provide evidence supporting the amyloid hypothesis of Alzheimer's disease.

The image shows a normal brain slice and a brain slice of with severe AD.

Featured Genetics Open Neuroscience Articles

·November 14, 2013·4 min read

Understanding a Protein’s Role in Familial Alzheimer’s Disease

Researchers use a novel genomic approach to better understand genetic mutations associated with familial Alzheimer's disease.

The image shows a dna double helix in a man's head.

Featured Genetics

·June 17, 2013·4 min read

Rare Genomic Mutations Found in Ten Families with Early-Onset, Familial Alzheimer’s Disease

A new study uncovers unique changes in DNA structure in genes important to neuronal function in relatives with early onset, familial Alzheimer's disease.