PINK1, a gene associated with Parkinson's disease, is not just responsible for the premature death of dopaminergic neurons, it also plays a key role in the neurogenesis of dopamine neurons throughout life.
Parkinson's patients carrying mutations in PINK1 and Parkin genes have increased levels of circulating interleukin 6 and mitochondrial DNA. The findings strengthen a link between genetic risk factors from Parkinson's disease and inflammation.
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Mice infected with bacteria that cause mild intestinal infections exhibited Parkinson's like symptoms later in life. The findings provide a pathophysiological model in which intestinal infections may act as a trigger for Parkinson's disease.
The MITOL protein has been implicated in Parkinson's disease.
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Findings from a mouse model study reveal Miro2 functions as a platform for Parkin translocation and damaged mitochondrial clearance.
Cardiff University researchers report a molecule in a common medication used to treat tapeworm has shown to be effective in enhancing the PINK1 protein and slowing the progression of Parkinson's disease.
Researchers uncover how the SNO reaction may contribute to the onset of Parkinson's disease.
A new study reveals a critical gene network involved in Parkinson's disease.
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Dietary Niacin can help boost levels of a compound associated with DNA repair, a new study reports.
Researchers have discovered a genetic mutation that could signify a risk for early onset of Parkinson's disease.
Researchers report two genes associated with Parkinson's disease are also key regulators of the immune system.
A new study reports stress on the endoplasmic reticulum, and not mitochondrial failure, results in neurodegeneration in Parkinson's disease.