PINK1, a gene associated with Parkinson's disease, is not just responsible for the premature death of dopaminergic neurons, it also plays a key role in the neurogenesis of dopamine neurons throughout life.
Parkinson's patients carrying mutations in PINK1 and Parkin genes have increased levels of circulating interleukin 6 and mitochondrial DNA. The findings strengthen a link between genetic risk factors from Parkinson's disease and inflammation.
Mice infected with bacteria that cause mild intestinal infections exhibited Parkinson's like symptoms later in life. The findings provide a pathophysiological model in which intestinal infections may act as a trigger for Parkinson's disease.
Cardiff University researchers report a molecule in a common medication used to treat tapeworm has shown to be effective in enhancing the PINK1 protein and slowing the progression of Parkinson's disease.
Dietary Niacin can help boost levels of a compound associated with DNA repair, a new study reports.
Researchers report two genes associated with Parkinson's disease are also key regulators of the immune system.
A new study reports stress on the endoplasmic reticulum, and not mitochondrial failure, results in neurodegeneration in Parkinson's disease.