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PINK1

This image shows the damage to mitochondria caused by Parkin.

Featured Genetics Neurology

·October 3, 2014·3 min read

Applying Proteomics to Parkinson’s

Researchers discover how unmutated versions of PINK1 and PARKIN collaborate to rid cells of damaged mitochondria.

The gut and brain are highlighted in this drawing of a man

Featured Genetics Neurology Neuroscience

·July 17, 2019·5 min read

Bacterial intestinal infections may trigger Parkinson’s disease

Mice infected with bacteria that cause mild intestinal infections exhibited Parkinson's like symptoms later in life. The findings provide a pathophysiological model in which intestinal infections may act as a trigger for Parkinson's disease.

Featured Neurology Open Neuroscience Articles

·January 10, 2017·3 min read

Boosting Dietary Niacin Could Benefit Those With Early Onset Parkinson’s

Dietary Niacin can help boost levels of a compound associated with DNA repair, a new study reports.

Diagram explains how PERK can cause cell death in parkinson's.

Featured Genetics Neurology

·June 23, 2016·4 min read

Challenging Current Views on Origins of Parkinson’s

A new study reports stress on the endoplasmic reticulum, and not mitochondrial failure, results in neurodegeneration in Parkinson's disease.

Featured Genetics Neurology Neuroscience Videos Open Neuroscience Articles

·February 17, 2017·3 min read

Discovery of Genetic Switch Could Help Prevent Parkinson’s Symptoms

A new study reveals a critical gene network involved in Parkinson's disease.

This MRI scan shows the location of the substantia nigra in the brain.

Featured Neurology

·August 16, 2013·4 min read

Effects of Parkinson’s Disease Mutation Reversed in Cells

Researchers discover a chemical in an anti-wrinkle cream could help prevent the death of nerve cells damaged by mutations, which cause an inherited form of Parkinson's disease.

Featured Genetics Neurology Open Neuroscience Articles

·November 25, 2015·3 min read

Enhancing Detection of Early Onset Parkinson’s Disease

Researchers find an increase in neural activity to stimulation in flies with genetic mutations associated with early onset Parkinson's disease.

Featured Genetics Neurology Open Neuroscience Articles

·November 21, 2017·5 min read

Good Cells Gone Bad

Researchers uncover how the SNO reaction may contribute to the onset of Parkinson's disease.

Featured Neurology

·October 14, 2020·2 min read

Links Between Inflammation and Parkinson’s Disease Highlighted

Parkinson's patients carrying mutations in PINK1 and Parkin genes have increased levels of circulating interleukin 6 and mitochondrial DNA. The findings strengthen a link between genetic risk factors from Parkinson's disease and inflammation.