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PINK1

Image shows a bag of walnuts.

Featured Neurology Open Neuroscience Articles

·January 10, 2017·3 min read

Boosting Dietary Niacin Could Benefit Those With Early Onset Parkinson’s

Dietary Niacin can help boost levels of a compound associated with DNA repair, a new study reports.

This image shows the differences in superior colliculus between Parkinson's patients and those without the disease.

Featured Neurology

·March 29, 2014·4 min read

New Parkinson’s Disease Chemical Messenger Discovered

Researchers identify a new chemical messenger that is critical for protecting the brain against PD.

This shows a cell with mitochondrial damage

Featured Genetics Neurology Neuroscience

·May 16, 2019·3 min read

Miro2 is a Parkin receptor for selective removal of damaged mitochondria

Findings from a mouse model study reveal Miro2 functions as a platform for Parkin translocation and damaged mitochondrial clearance.

Featured Genetics Neurology Open Neuroscience Articles

·November 21, 2017·5 min read

Good Cells Gone Bad

Researchers uncover how the SNO reaction may contribute to the onset of Parkinson's disease.

This shows dopamine neurons

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·March 23, 2021·4 min read

Parkinson’s Gene May Impair How New Neurons Are Made Throughout Our Lifetime

PINK1, a gene associated with Parkinson's disease, is not just responsible for the premature death of dopaminergic neurons, it also plays a key role in the neurogenesis of dopamine neurons throughout life.

Image shows dysfunctional lysomes in parkinson's model.

Featured Neurology

·September 16, 2015·5 min read

Rapamycin Prevents Parkinson’s Disease in Mouse Model

According to a new study, an FDA approved drug prevented the development of Parkinson's disese in mice genetically engineered to develop the neurodegenerative disorder.

This is an illustration of PINK1 removing mitochondria.

Featured Genetics Neurology

·August 12, 2015·3 min read

New Potential Pathway for Treating ALS and Parkinson’s Diseases

A new study reports PINK1 triggers mitophagy, a process which breaks down and removes damaged mitochondria from cells.

Image shows a neuron without PINK1.

Featured Neurology

·June 27, 2016·5 min read

Overactive Immune System May Be Responsible for Cell Death in Parkinson’s

Researchers report two genes associated with Parkinson's disease are also key regulators of the immune system.

Diagram explains how PERK can cause cell death in parkinson's.

Featured Genetics Neurology

·June 23, 2016·4 min read

Challenging Current Views on Origins of Parkinson’s

A new study reports stress on the endoplasmic reticulum, and not mitochondrial failure, results in neurodegeneration in Parkinson's disease.

This shows mitochondria from iPSC-derived dopaminergic neurons.

Featured Genetics Open Neuroscience Articles

·April 2, 2015·3 min read

Mitochondria Are Altered in Human Cell Model of Parkinson’s Disease

Using stem cells derived from Parkinson's patients, researchers confirm mitochondrial changes.

artoon of a fly watching TV.

Featured Genetics Neurology Open Neuroscience Articles

·November 25, 2015·3 min read

Enhancing Detection of Early Onset Parkinson’s Disease

Researchers find an increase in neural activity to stimulation in flies with genetic mutations associated with early onset Parkinson's disease.

Image shows DNA strands.

Featured Genetics Neurology Neuroscience Videos Open Neuroscience Articles

·February 17, 2017·3 min read

Discovery of Genetic Switch Could Help Prevent Parkinson’s Symptoms

A new study reveals a critical gene network involved in Parkinson's disease.

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