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PINK1

This shows dopamine neurons

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·March 23, 2021·4 min read

Parkinson’s Gene May Impair How New Neurons Are Made Throughout Our Lifetime

PINK1, a gene associated with Parkinson's disease, is not just responsible for the premature death of dopaminergic neurons, it also plays a key role in the neurogenesis of dopamine neurons throughout life.

This is a diagram from the study

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·October 14, 2020·2 min read

Links Between Inflammation and Parkinson’s Disease Highlighted

Parkinson's patients carrying mutations in PINK1 and Parkin genes have increased levels of circulating interleukin 6 and mitochondrial DNA. The findings strengthen a link between genetic risk factors from Parkinson's disease and inflammation.

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·November 21, 2017·5 min read

Good Cells Gone Bad

Researchers uncover how the SNO reaction may contribute to the onset of Parkinson's disease.

Image shows DNA strands.

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·February 17, 2017·3 min read

Discovery of Genetic Switch Could Help Prevent Parkinson’s Symptoms

A new study reveals a critical gene network involved in Parkinson's disease.

Image shows a brain.

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·December 12, 2017·3 min read

Tapeworm Drug May Help in Fight Against Parkinson’s

Cardiff University researchers report a molecule in a common medication used to treat tapeworm has shown to be effective in enhancing the PINK1 protein and slowing the progression of Parkinson's disease.

This image shows the damage to mitochondria caused by Parkin.

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·October 3, 2014·3 min read

Applying Proteomics to Parkinson’s

Researchers discover how unmutated versions of PINK1 and PARKIN collaborate to rid cells of damaged mitochondria.

This is an illustration of PINK1 removing mitochondria.

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·August 12, 2015·3 min read

New Potential Pathway for Treating ALS and Parkinson’s Diseases

A new study reports PINK1 triggers mitophagy, a process which breaks down and removes damaged mitochondria from cells.

This image shows the differences in superior colliculus between Parkinson's patients and those without the disease.

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·March 29, 2014·4 min read

New Parkinson’s Disease Chemical Messenger Discovered

Researchers identify a new chemical messenger that is critical for protecting the brain against PD.

This image shows a Parkin expressing neuron undergoing apoptosis.

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·November 13, 2014·3 min read

Researchers Make Breakthrough in Understanding Parkinson’s Disease

A gene implicated in Parkinson's disease can control the repair or destruction of neurons, a new study reports.

A drawing of a brain is shown here

Featured Genetics Neurology

·May 20, 2019·3 min read

Researchers link new protein to Parkinson’s

The MITOL protein has been implicated in Parkinson's disease.

Diagram explains how PERK can cause cell death in parkinson's.

Featured Genetics Neurology

·June 23, 2016·4 min read

Challenging Current Views on Origins of Parkinson’s

A new study reports stress on the endoplasmic reticulum, and not mitochondrial failure, results in neurodegeneration in Parkinson's disease.

This shows mitochondria from iPSC-derived dopaminergic neurons.

Featured Genetics Open Neuroscience Articles

·April 2, 2015·3 min read

Mitochondria Are Altered in Human Cell Model of Parkinson’s Disease

Using stem cells derived from Parkinson's patients, researchers confirm mitochondrial changes.

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