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parvalbumin

Featured Neuroscience Open Neuroscience Articles

·October 5, 2017·5 min read

Mouse Cell Type Census Reveals Gender Specific Brain Differences

A multiyear study reveals, contrary to expectations, numbers and ratios of three major inhibitory cell types vary stereo-typically across different cortical parts. Additionally, researchers identified 11 subcortical areas with gender specific differences in mice.

Autism Featured Neuroscience Psychology

·August 3, 2017·6 min read

Autism May Reflect Excitation-Inhibition Imbalance in Brain

Reducing the excitation-inhibition ratio by diminishing excitability of pyramidal neurons or increasing excitability of PV neurons led mice to spend more time engaged in social encounters. Researchers believe the excitation-inhibition balance may play a key role in autism and normal social behavior.

Featured Psychology

·July 17, 2017·4 min read

Brain Circuit Study Finds Key Links to Depressive Symptoms

Researchers have discovered a link between specific neural circuits to distinct behavioral symptoms of depression. The study, published in Cell, reports altering the networks helped to improve symptoms such as social withdrawal and helplessness.

Featured Neurology

·May 9, 2017·4 min read

Neuronal Targets That Restore Movement in Model of Parkinson’s Disease Discovered

A new optogenetics study has revealed two groups of neurons that can be turned on and off to alleviate movement related symptoms of Parkinson's disease.

Featured Neuroscience Open Neuroscience Articles

·April 7, 2017·4 min read

Sleep on It: Researchers Find What Makes Memories Tick

Researchers report on how sleep deprivation affects the ability to form new memories.

Featured Neuroscience

·September 22, 2016·5 min read

Innovative Tools Will Shed Clarifying Light on Inhibitory Neurons

Researchers have developed a new method that combines genetic markers and virus particles to target GABA cell types with a high degree of specificity.

Image shows pv interneurons associated with fear.

Featured Neuroscience Psychology

·July 14, 2016·4 min read

Specialized Neurons in Brain Area Associated with Emotional Memory Play Role in Fear

According to a new study, fear memory encoding is influences by parvalbumin interneurons in the amygdala.

Featured Neuroscience

·May 10, 2016·4 min read

Early Life Stress Accelerates Maturation of Key Brain Region in Male Mice

A new study of mice finds early exposure to stress can make specific brain regions mature faster.

Featured Neuroscience

·February 4, 2016·4 min read

Brain Formation Pattern Shows Why Early Trauma May Leave No Clues

Researchers report many PV defects could have their origin, not during adult life, but instead in the SST templates that set circuit parameters in the first place.

Featured Psychology

·February 6, 2013·2 min read

Induction of Mild Inflammation Leads to Cognitive Deficits Related to Schizophrenia

Researchers have identified an exceptional mouse model of schizophrenia. The study identified a mutant mouse lacking the Schnurri-2 protein (Shn-2 KO) that exhibits behavioral deficits and other brain features consistent with schizophrenia.

The image is a topography of the primary motor cortex, on an outline drawing of the human brain. Different body parts are listed in this area.

Featured Neurology

·February 5, 2013·3 min read

Stroke Damage in Mice Overcome by Training Which ‘Rewires’ Brain Centers

A new study discovers mice can recover from physically debilitating strokes that damage the primary motor cortex, if the rodents are quickly subjected to physical conditioning that rapidly “rewires” a different part of the brain to take over lost function.