pain

This shows a brain

Molecular link between chronic pain and depression revealed

Inhibitory inputs to the neural circuit between the dorsolateral bed nucleus of the stria terminalis (dlBNST) to the ventral tegmental area (VTA) increase when a person is in chronic pain. This alteration is mediated by enhanced corticotropin-releasing factor signaling within the dlBNST, leading to suppression of the mesolimbic dopaminergic system. The result is depressive mood and anhedonia associated with chronic pain.... Read More...
These brain scans shows the foot area highlighted

Hit it where it hurts: Scientists reveal how mirrors cure phantom pain

Visual responsiveness in the somatosensory cortex diminishes significantly following mirror therapy for phantom limb pain. Before therapy, researchers discovered a strong, unexpected activation in the sensorimotor foot region of amputees to visually presented images of the foot. This response was no longer present following mirror therapy.... Read More...