Brain mechanisms have potential to block arthritis pain
Researchers discover the amygdala is a critical site of action for pain modulation. An existing compound, LY379268, provides pain-relieving effects and helps to reduce anxiety.... Read More...
pain
Molecular link between chronic pain and depression revealed
Inhibitory inputs to the neural circuit between the dorsolateral bed nucleus of the stria terminalis (dlBNST) to the ventral tegmental area (VTA) increase when a person is in chronic pain. This alteration is mediated by enhanced corticotropin-releasing factor signaling within the dlBNST, leading to suppression of the mesolimbic dopaminergic system. The result is depressive mood and anhedonia associated with chronic pain.... Read More...
Persistent headache or back pain ‘twice as likely’ in the presence of the other
Researchers have identified a positive association between persistent lower back pain and headache disorders. The study reveals those with persistent back pain or persistent headache disorders are twice as likely to suffer from both disorders at the same time.... Read More...
Migraine sufferers needlessly enduring agonizing pain
Many people who suffer migraines are often diagnosed with other conditions. For those with a clinical diagnosis, many are unaware of treatment options available for pain and to slow the frequency of attacks.... Read More...
Skyrocketing interest in marijuana and cannabinoids for pain
37% of Millenials and 25% of Gen Xers say they have used cannabinoids to help relieve pain. ... Read More...
Scorpion toxin that targets ‘wasabi receptor’ may help solve mystery of chronic pain
WaTx, a short protein in the venom of Australian Black Rock scorpions, is helping researchers uncover new information about chronic pain and inflammation. ... Read More...
Cannabis flower is an effective mid-level analgesic medication for pain
People who used while dried cannabis flowers or cannabis with higher levels of THC had the greatest analgesic response to pain. Those who used CBD reported lower levels of pain relief.... Read More...
New pain organ discovered in the skin
In a groundbreaking finding, researchers have identified a new sensory organ under the skin that can detect pain as a result of impact or pinpricks. The organ comprises of glial cells with multiple long protrusions which collectively make up the mesh-like organ under the skin.... Read More...
Too much coffee raises the odds of triggering a migraine headache
Drinking three or more cups of coffee a day can trigger the onset of a headache for patients with episodic migraines.... Read More...
Skin nerves anticipate and fight infection: New type of immunity discovered
Mouse study reveals pain-sensing neurons also help fight skin infections and help prevent its spread. The findings suggest a new type of immunity. ... Read More...
Researchers unlock access to pain relief potential of cannabis
The cannabis plant creates anti-inflammatory and pain-relieving molecules that are 30 times more powerful than Aspirin.... Read More...
Hit it where it hurts: Scientists reveal how mirrors cure phantom pain
Visual responsiveness in the somatosensory cortex diminishes significantly following mirror therapy for phantom limb pain. Before therapy, researchers discovered a strong, unexpected activation in the sensorimotor foot region of amputees to visually presented images of the foot. This response was no longer present following mirror therapy.... Read More...