Conolidine, a natural pain killer derived from the pinwheel flower and frequently used in Chinese medicine, interacts with a newly identified opioid receptor that regulates natural opioid peptides produced in the brain.
Study reveals there is no significant uptick in men who played high school football reporting problems with brain health in middle age compared to their peers who did not play sports. However, ex-football players were more likely to experience sleep problems and be prescribed medications for chronic pain during mid-life.
Study identifies six psycho-acoustically distinct types of screams, relaying emotions such as pain, anger, fear, joy, sadness, and pleasure. Non-alarming screams, such as expressions of joy and pleasure, are perceived and processed by the brain more effectively than screams of alarm.
Genetics may help explain why women are at higher risk for developing chronic pain disorders than men. The study also sheds light on the role the central nervous system plays in the development of chronic pain.
Findings reveal female patients were perceived to be in less pain than males who reported and exhibited the same level of pain intensity.
Focusing attention on a neural pathway starting at the periaqueductal grey region of the midbrain, researchers made a novel discovery about how dopamine generates different pain responses in male and female mice. Findings indicate dopamine may reduce pain sensitivity in males, whereas, in females, dopamine helps focus attention elsewhere in the presence of pain.