Researchers report activating a pathway between the amygdala and brain stem helps to relieve pain and reduce defensive behaviors in rat models.
In the first year after a diagnosis of multiple sclerosis, 60% of patients experience fatigue, 50% experience pain, 47% have symptoms of depression, and 39% report increased anxiety. Researchers say urgent, non-pharmaceutical therapies should be provided for newly diagnosed MS patients to help reduce both pain and mental health symptoms.
An infusion of the local anesthetic Lidocaine may provide relief to patients with chronic migraines that do not respond to other medications.
Researchers uncover the mechanism behind how a subset of NSAIDs reduces inflammation, which helps explain some of the curious side effects of the anti-inflammatories.
Most cancer patients who used medical cannabis reported a significant improvement in pain measures and a decrease in some other cancer-related symptoms. Additionally, medical cannabis use reduced the consumption of traditional, opioid-based pain killers for those with cancer.
Gene therapy that inhibits targeted nerve cell signals effectively improves symptoms of neuropathic pain without negative side effects in mouse models of spinal cord injury or peripheral nerve damage.