An examination of brainstems from children and young adults constantly exposed to air pollution reveals markers of Alzheimer's disease, Parkinson's disease, and motor neuron disease. Findings suggest air pollution poses risks of serious neurological damage from an early age.
Death caused as a result of sleep deprivation is preceded by the accumulation of reactive oxidative species in the gut.
Regular exercise may help prevent or reduce the severity of ARDS for those with coronavirus. A single session of exercise increases the production of a critical antioxidant, called EcSOD, helping to reduce the effects of COVID-19 infection.
A new method called Tox-seq found only one sub-group of microglia caused oxidative stress. The gene expression signatures of this sub-group from a mouse model matched patterns observed in cells suspected of causing damage in progressive multiple sclerosis patients. The pattern of gene expression associated with oxidative stress in mouse cells included genes involved in coagulation.
Exposure to low levels of air pollution over a decade led to changes in gene expression associated with morbidity and mortality in the longer term.
Adding walnuts to your diet could help protect against age-related cognitive decline, a new study reports. Walnuts contain polyphenols and omega-3 fatty acids, which counteract the oxidative stress and inflammation that contribute to cognitive decline.
Mouse models and human postmortem brain tissue sample studies reveal a subtype of schizophrenia is related to abnormally high levels of hydrogen sulfide in the brain. Hair follicle analysis of patients with this schizophrenia subtype revealed higher expression of MPST mRNA than in those without the condition. MPST is linked to the production of hydrogen sulfide. The findings may lead to new tests to determine if a patient has the schizophrenia subtype from a simple hair sample analysis.
Eating cheese and increasing consumption of other dairy products helps improve vascular health by reducing the effects of a high-sodium diet, a new study reports.
Bilirubin, a bile pigment most commonly associated with jaundice in newborns, appears to have neuroprotective properties. A new study in mice reveals bilirubin may protect the brain against oxidative stress.
Older adults who consume tart cherry juice daily may have improved cognitive function. Researchers believe this may be due to anti-oxidative and anti-inflammatory properties of the cherries.
Maternal exposure to higher levels of air pollution is associated with lower IQ scores in their children. For those whose mothers were in the highest 10% of exposure had IQ score that were, on average, 2.5 points lower than those whose mothers were in the lowest 10%. However, higher maternal folate levels appear to neurtralize the effect of high pollution exposure on offspring.
N-acetylcysteine (NAC) appears to positively affect the dopaminergic system, helping to improve symptoms in those with Parkinson's disease.