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oxidative stress

Autism Featured Neuroscience Open Neuroscience Articles Psychology

·November 5, 2025·7 min read

Oxidative Stress May Drive Repetitive Behaviors Linked to Autism, OCD

A new study shows that oxidative stress—an imbalance between damaging molecules and antioxidants—may contribute to repetitive behaviors observed in mice, similar to those seen in autism spectrum disorder and schizophrenia. Researchers found that higher levels of oxidative stress biomarkers, including glutathione and specific proteins, were linked to more severe stereotypies in young mice.

Featured Genetics Neurology Neuroscience

·November 3, 2025·5 min read

Antioxidant Defense System in the Brain Discovered

A new study identifies biliverdin reductase A (BVRA) as a crucial enzyme defending neurons from oxidative stress, acting independently of its traditional role in bilirubin production. Using genetically modified mice, researchers found that BVRA binds directly to NRF2, a master regulator of antioxidant defense, ensuring the activation of protective genes that maintain cellular health.

Brain Cancer Featured Neuroscience

·October 11, 2024·4 min read

Ferroptosis Findings Offer Hope for Cancer and Cell Protection

Scientists have uncovered a new pathway regulating cell death, or ferroptosis, which could pave the way for innovative cancer treatments. By examining how oxidative stress damages lipid membranes, the team found that the proteasome recycling system becomes clogged, accelerating cell destruction.

This shows a stressed woman with gray hair.

Featured Genetics Neuroscience Psychology

·October 7, 2024·6 min read

Does Stress Lead to Premature Hair Graying?

Hair turns grey due to a decrease in melanin production in hair follicles, a process influenced by both genetics and environmental factors like stress. Contrary to myths, plucking a grey hair won’t make more grow back, and hair can’t turn grey overnight.

Featured Neurology Neuroscience

·August 30, 2024·5 min read

Tau May Protect Brain Cells from Oxidative Damage

Researchers have discovered that the Tau protein, often linked to neurodegenerative diseases like Alzheimer's, also has a protective role in the brain. Tau helps combat oxidative stress by aiding in the formation of lipid droplets in glial cells, which sequester toxic lipids and protect neurons.

Featured Neuroscience Open Neuroscience Articles

·November 7, 2022·5 min read

Motivation Is Affected by Oxidative Stress, but Nutrition Can Help

Higher levels of glutathione in the nucleus accumbens correlated with better and more steady performance in motivation-based tasks. Findings suggest improvements in accumbal anti-oxidant function that can be acquired via diet or supplementation may be a feasible approach to help boost motivation.

Featured Genetics Neuroscience

·July 1, 2022·5 min read

Researchers Uncover New Pathway for Accumulation of Age-Promoting ‘Zombie Cells’

Oxidative damage to telomeres can trigger cellular senescence. The findings could lead to the development of new therapeutics for healthy aging and to combat cancers.

Featured Neuroscience Open Neuroscience Articles Psychology

·April 13, 2022·5 min read

High Cardiovascular Risk Is Associated With Symptoms of Depression

Depression and cardiovascular disease appear to be closely related due to their links to inflammation and oxidative stress. Researchers say lowering the risks of cardiovascular disease can improve symptoms of depression.

This shows hepcidin expression in the brain

Featured Neurology Neuroscience Open Neuroscience Articles

·February 1, 2022·4 min read

Iron Accumulation Linked With Age-Related Cognitive Decline

A breakdown in regulatory mechanisms causes iron to build up in the brain during aging, increasing oxidative stress and increasing the risk of age-related cognitive decline, a new study reports.

This shows a man clutching his head in pain

Featured Neurology Neuroscience

·November 19, 2021·5 min read

Plant Based Diet May Ease Chronic Migraine Severity

Switching to a diet that includes more leafy greens, including spinach and kale, reduces inflammation and oxidative stress, and improved symptoms associated with chronic migraine.

Featured Neurology Neuroscience

·November 10, 2021·4 min read

New Insights on ALS May Point To a Potentially Promising Treatment Strategy

Post-mortem studies of brain tissue from ALS patients reveal an abnormal form of tau is present in novel brain areas, and the tau interacts with DRP1. The tau appears to cause the brain cell's mitochondria to fragment and increase oxidative stress. Reducing tau reversed the effect, decreasing oxidative stress and mitochondrial fragmentation.

Featured Neurology Neuroscience Open Neuroscience Articles

·October 22, 2021·4 min read

Fat Cells Found to Play a Central Role in Cognitive Decline and Neurodegeneration

A new study reveals how adipocytes, or fat cells, play a role in cognitive decline and increased neurodegeneration risks. Using genetically modified mouse models, researchers found oxidative stress through exposure to a Western diet increased the production of inflammatory cytokines confined to adipocytes and altered protein markers of memory and cognition in the hippocampus.

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oxidative stress

Oxidative Stress May Drive Repetitive Behaviors Linked to Autism, OCD

Antioxidant Defense System in the Brain Discovered

Ferroptosis Findings Offer Hope for Cancer and Cell Protection

Does Stress Lead to Premature Hair Graying?

Tau May Protect Brain Cells from Oxidative Damage

Motivation Is Affected by Oxidative Stress, but Nutrition Can Help

Researchers Uncover New Pathway for Accumulation of Age-Promoting ‘Zombie Cells’

High Cardiovascular Risk Is Associated With Symptoms of Depression

Iron Accumulation Linked With Age-Related Cognitive Decline

Plant Based Diet May Ease Chronic Migraine Severity

New Insights on ALS May Point To a Potentially Promising Treatment Strategy

Fat Cells Found to Play a Central Role in Cognitive Decline and Neurodegeneration

What Triggers Tantrums? Sensory Overload May Be To Blame

Brain Circuit That Forces Behavior Into “Repeat Mode” Identified

Genetics Plus Heart Health Markers Sharpen Dementia Risk

Supplement Shows Promise in Blocking Amyloid in Alzheimer’s

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