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          opioid system

          This shows a brain and pills.
          FeaturedNeurologyNeurosciencePain
          ·May 24, 2025·4 min read

          Placebo Triggers Brain’s Opioid System to Relieve Pain

          Researchers have successfully induced the placebo effect in rats, uncovering the neural mechanisms behind how belief in pain relief can reduce the perception of pain. Using conditioning, rats learned to associate injections with pain relief, and later exhibited reduced pain responses even when injected with saline.
          Read More
          This shows a woman in headphones and a brain.
          FeaturedNeurologyNeuroscience
          ·April 16, 2025·4 min read

          Music-Induced “Chills” Trigger Natural Opioids in the Brain

          Listening to favorite music activates the brain’s opioid system, which is involved in feelings of pleasure and pain relief, according to a new PET imaging study. Researchers found that music-induced “chills” are linked to the release of natural opioids in key brain areas.
          Read More
          This shows neuroimaging of brain regions
          FeaturedNeuroscienceOpen Neuroscience Articles
          ·September 2, 2021·3 min read

          A Connection Between Brain’s Opioid System and Eating Behavior

          The function of the opioid system is connected to eating triggered by external stimuli. The findings could lead to the development of new therapies that target the opioid system to reduce obesity.
          Read More
          This shows brain scans from the study
          FeaturedNeurosciencePsychology
          ·June 16, 2020·2 min read

          The molecular mechanisms of depression

          Study reveals how the brain's opioid system is linked to mood changes associated with depression and anxiety. Neuroimaging revealed, in those with depression, there is a decreased number of opioid receptors in specific areas of the brain.
          Read More
          This shows colorful macaroon cakes
          FeaturedNeuroscienceOpen Neuroscience Articles
          ·January 14, 2020·4 min read

          Sugar changes the chemistry of your brain

          After 12 days of sugar intake, researchers noted major changes in both the dopamine and opioid systems of pigs' brains. Alterations in the opioid system were seen following the very first intake of sugar.
          Read More
          This shows a brain
          FeaturedNeurosciencePsychology
          ·May 24, 2019·2 min read

          Short-term use of opioids increases subjective pleasure

          Short-term opioid use increases positive emotional experiences by intensifying feelings of pleasure and weakening negative emotions. This, researchers say, could be a contributing factor for later opioid addiction. However, the long term use of opioids alters the reward system, diminishing the initial sensitivity and blunting emotions.
          Read More
          a brain
          FeaturedNeurosciencePsychology
          ·August 29, 2018·7 min read

          Ketamine’s Antidepressant Effects Tied to Opioid System in the Brain

          Researchers report ketamine's antidepressive effects require activation of opioid receptors in the brain. The study highlights the interaction between depression, pain and opioid addiction.
          Read More
          Image shows people laughing.
          FeaturedNeurosciencePsychology
          ·June 2, 2017·4 min read

          Social Laughter Releases Endorphins in the Brain

          Researchers uncover how laughter releases endorphins in the brain.
          Read More
          Image shows a woman listening to music.
          Auditory NeuroscienceFeaturedNeuroscienceOpen Neuroscience ArticlesPsychology
          ·February 8, 2017·3 min read

          Sex, Drugs, and Rock & Roll Chemistry in the Brain

          Using a drug used to help treat addiction, researcher report exposing people to their favorite songs no longer elicit feelings of pleasure.
          Read More
          The image shows the opiod system in the brain.
          FeaturedPsychology
          ·October 10, 2013·5 min read

          Sticks and Stones: Brain Releases Natural Painkillers During Social Rejection

          Researchers find the opioid system responds to social rejection, not just physical pain.
          Read More
          The diagram shows the location of the amygdala in the brain.
          FeaturedNeuroscience
          ·June 12, 2013·4 min read

          Researchers Point to Brain’s ‘Dark Side’ as Key to Cocaine Addiction

          A new study provides evidence that the central amygdala, an area of the brain associated with emotion, plays a major role in sustaining cocaine addiction.
          Read More

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          This shows a robot yawning with chimps in the background.

          Robot Yawns Spark Contagious Yawning in Chimps

          This shows a woman sleeping.

          Conquering Nightmares and Insomnia with Science

          This shows a brain and a scale.

          Obeying Orders Lowers Moral Responsibility Perception in the Brain

          This shows a head and a brain.

          Brain Area Stores and Resolves Hypotheses for Landmark Ambiguity

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