Glutamatergic neural connections between the prelimbic prefrontal cortex and nucleus accumbens appear to be responsible for co-morbid anxiety and OCD behaviors.
Neuroimaging predicts whether a person with OCD will respond to stress-reduction therapy or exposure-based therapy best. Analyzing brain activity may help to provide tailored treatments to individuals suffering from OCD.
People with OCD have six times higher Immuno-moodulin (Imood) expression that those without the disorder. Blocking Imood with the aid of an antibody reduced OCD-like behaviors in mouse models within a couple of days following treatment.
Those with obsessive-compulsive disorder (OCD) may place less trust in their previous experiences, increasing uncertainty, indecisiveness, and repetitive behaviors.
The famous rubber hand illusion may help people with OCD overcome their condition without the stress of exposure therapy.
Mice with dysfunctional Hoxb8-lineage microglia exhibited excessive overgrooming behaviors that resemble trichotillomania in humans. Female sex hormones also caused more severe OCD-like behaviors and increased anxiety in the mouse models.
Following a month of treatment with deep transcranial magnetic stimulation (dTMS), people with OCD reported a 45.2% reduction in symptom severity.
Orthorexia Nervosa, an eating disorder associated with a pathological obsession with healthy eating, has been associated with OCD traits, poor body image, preoccupation with personal appearance and a prior history of eating disorders. Researchers report those who practise vegetarianism or veganism are at an increased risk of developing orthorexia.
Study finds a correlation between the construct of personal responsibility and an increased risk of developing OCD and generalized anxiety disorder.
Optogenetic stimulation causes signals in the sensory cortex to halt actions during a behavioral task, while altering signals in the motor cortex to cause mice to act more impulsively.
Researchers discuss the potential of deep brain stimulation in the treatment of Parkinson's disease, OCD, Tourette syndrome and other disorders.
According to a new study, 67% of pregnant women under the age of 25 in London suffer from mental health disorders such as depression, anxiety and PTSD. Based on the findings, researchers suggest more could be done to target prenatal mental health services for younger women.
