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          NMDA

          This shows a diagram of a brain
          FeaturedNeurosciencePsychology
          ·December 30, 2022·4 min read

          Ketamine Found to Increase Brain Noise

          By inhibiting NMDA receptors, ketamine increases noise to gamma frequencies in one layer of the thalamic nucleus and one lay of the somatosensory cortex. Findings suggest psychosis may be triggered by an increase in background noise impairing thalamocortical neurons which may be caused by a malfunction in NMDA receptors affecting the balance of inhibition and excitation in the brain.
          Read More
          This shows a finger touching a drawing of a brain
          FeaturedNeuroscience
          ·December 2, 2022·4 min read

          How Ketamine Acts as a ‘Switch’ in the Brain

          Ketamine alters neural activity in the cerebral cortex, silencing normally active neurons and activating neurons that are normally inactive. The ketamine activity-induced "switch" in brain regions associated with depression may help explain its treatment effects.
          Read More
          This shows filopodia
          FeaturedNeuroscience
          ·November 30, 2022·7 min read

          Silent Synapses Are Abundant in the Adult Brain

          The adult brain contains millions of "silent synapses", or immature connections between neurons that remain inactive until they are required for learning new information and storing new memories.
          Read More
          This shows the outline of a head made up of bubbles
          FeaturedNeuroscienceOpen Neuroscience ArticlesPsychology
          ·April 16, 2022·6 min read

          Modulating NMDA Receptor Activity Is the Key to Successful Treatment of PTSD

          NYX-783, a newly discovered drug, helps modulate NMDA receptor function in neurons. The drug appears to be effective at suppressing the return of PTSD symptoms in rodent models.
          Read More
          This shows a rat
          FeaturedNeuroscience
          ·October 22, 2021·5 min read

          VR Experiment With Rats Offers New Insights About How Neurons Enable Learning

          Studying rats in a virtual reality maze, researchers discover certain hippocampal neurons play a vital role in a specific mechanism of navigation.
          Read More
          This shows a neuron
          FeaturedGeneticsNeurologyOpen Neuroscience Articles
          ·June 24, 2020·3 min read

          Genetic malfunction of brain astrocytes triggers migraine

          Familial hemiplegic migraine type 2 (FHM2) causes a malfunction of astrocytes in the cingulate cortex. Manipulating astrocytes in the cingulate cortex reversed the disfunction, preventing an increase in migraine-like symptoms in mice carrying the FHM2 defect.
          Read More
          This shows a brain
          FeaturedNeurosciencePsychology
          ·June 5, 2020·3 min read

          NMDA receptors may link psychosis and sleep deficits

          NMDA receptor hypofunction is involved in the reduction of sleep spindles and delta oscillations, which appear in the brain during deep natural sleep. Findings confirm the role NMDA receptors play in sleep disorders that accompany psychotic states.
          Read More
          This shows a synapse
          FeaturedGeneticsNeuroscienceOpen Neuroscience Articles
          ·March 11, 2020·2 min read

          JNK protein triggers neurons to withdraw their synapses when stressed

          Using optogenetics to inhibit the JNK protein prevented synapses from shrinking in response to stress.
          Read More
          This shows synaptic transmission in action
          FeaturedNeuroscienceOpen Neuroscience ArticlesPsychology
          ·February 24, 2020·4 min read

          Antibodies: The body’s own antidepressants

          When autoantibodies are able to enter the bran and act on NMDA receptors, people experience relief from symptoms of anxiety, depression, and stress.
          Read More
          This shows a glass with ice cubes
          FeaturedNeuroscienceOpen Neuroscience Articles
          ·November 26, 2019·5 min read

          One shot of ketamine could reduce problem drinking

          A single shot of ketamine administered to heavy drinkers following reactivation of their drinking memories led to a rapid decrease in the urge to drink. The effect lasted for over nine months.
          Read More
          This shows neurons
          FeaturedNeurologyNeuroscience
          ·August 16, 2019·4 min read

          More Than Just Jaundice: Bilirubin May Protect The Brain

          Bilirubin, a bile pigment most commonly associated with jaundice in newborns, appears to have neuroprotective properties. A new study in mice reveals bilirubin may protect the brain against oxidative stress.
          Read More
          This shows a depressed woman
          FeaturedNeurosciencePsychology
          ·July 31, 2019·4 min read

          Ketamine isn’t an opioid and treats depression in a unique way

          A new study clarifies the mechanism behind how ketamine works as an antidepressant. Researchers say there is evidence to suggest ketamine binds to NMDA receptors, instead of opioid receptors. Reducing the belief that ketamine is an opioid may make patients with depression more open to using the treatment.
          Read More
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          This shows a person meditating.

          Meditation Diminishes Bias Toward Negative Information

          This shows a pregnant woman.

          AI Can Predict Preterm Birth at 31 Weeks of Gestation

          This shows a middle aged man.

          Middle Age Sexual Satisfaction: A Potential Early Sign of Cognitive Decline

          This shows sleeping heads.

          Sleep Apnea’s Deep Impact on Gene Activity

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