NMDA

Targeting ‘Hidden Pocket’ For Treatment of Stroke and Seizure

Neuroscience NewsJanuary 20, 2019

Study reveals a motif on the 93-series compound fits into a tiny pocket within the NMDA receptor. The findings could lead to new treatment options for stroke and seizures, researchers report. ... Read More...

FeaturedNeurologyOpen Neuroscience Articles5 min read

New Key Mechanism of Epileptic Seizures Revealed

Neuroscience NewsJanuary 7, 2019

According to a new mathematical model of seizures, only the conductivity of the AMPA receptors in neurons in the temporal lobe significantly change, leading to stronger excitation and synaptic signals.... Read More...

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Ketamine’s Antidepressant Effects Tied to Opioid System in the Brain

Neuroscience NewsAugust 29, 2018

Researchers report ketamine's antidepressive effects require activation of opioid receptors in the brain. The study highlights the interaction between depression, pain and opioid addiction. ... Read More...

FeaturedNeurosciencePsychology9 min read

Early Sensory Stimulation is Critical for the Development of Sensory Networks

Neuroscience NewsAugust 11, 2018

A new study reports sensory stimulation during the first two weeks of life is critical for establishing brain networks that help map sensation.... Read More...

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PSD as a Molecular Platform For Understanding Synapse Formation and Plasticity

Neuroscience NewsAugust 10, 2018

A new study reports that both in solution and on supported membrane bilayers, multivalent interaction networks formed by major excitatory postsynaptic density scaffold proteins led to formation of PSD-like assemblies via phase separation.... Read More...

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Targeting a Brain Mechanism Could Help Treat Aggression

Neuroscience NewsAugust 10, 2018

Researchers have identified some of the key neurobiological mechanisms that help keep aggression under control. The findings could help develop targeted treatments to help those with aggressive problems associated with psychological disorders.... Read More...

FeaturedNeuroscienceOpen Neuroscience ArticlesPsychology6 min read

Alzheimer’s Drug May Stop Disease If Used Before Symptoms Appear

Neuroscience NewsAugust 1, 2018

Researchers report memantine, an FDA approved drug, may not only alleviate symptoms of mild Alzheimer's disease, but could also prevent progression of the disease if used before symptoms appear. ... Read More...

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How Experience Changes Basics of Memory Formation

Neuroscience NewsJuly 23, 2018

Researchers report animals with previous conditioned experiences form memories using different plasticity mechanisms to naive subjects, even if they are about to learn the same thing.... Read More...

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New Insight Into How Autism Might Develop in the Brain

Neuroscience NewsJune 26, 2018

Researchers have identified a new molecular mechanism that may play a role in the development of autism.... Read More...

AutismFeaturedGeneticsOpen Neuroscience Articles5 min read

Ketamine Acts Fast to Treat Depression and Its Effects Last, But How?

Neuroscience NewsJune 22, 2018

Researchers explore the mechanisms behind ketamine's effectiveness at treating depression. The study reports the long lasting effects of ketamine may be due to G proteins timing in moving back to lipid rafts.... Read More...

FeaturedNeurosciencePsychology6 min read