According to a new mathematical model of seizures, only the conductivity of the AMPA receptors in neurons in the temporal lobe significantly change, leading to stronger excitation and synaptic signals.
Researchers report ketamine's antidepressive effects require activation of opioid receptors in the brain. The study highlights the interaction between depression, pain and opioid addiction.
A new study reports sensory stimulation during the first two weeks of life is critical for establishing brain networks that help map sensation.
A new study reports that both in solution and on supported membrane bilayers, multivalent interaction networks formed by major excitatory postsynaptic density scaffold proteins led to formation of PSD-like assemblies via phase separation.
Researchers have identified some of the key neurobiological mechanisms that help keep aggression under control. The findings could help develop targeted treatments to help those with aggressive problems associated with psychological disorders.
Researchers report memantine, an FDA approved drug, may not only alleviate symptoms of mild Alzheimer's disease, but could also prevent progression of the disease if used before symptoms appear.
Researchers explore the mechanisms behind ketamine's effectiveness at treating depression. The study reports the long lasting effects of ketamine may be due to G proteins timing in moving back to lipid rafts.
Researchers have identified a new mechanism controlling the migration of neurons during brain development.