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NMDA

·July 10, 2019·3 min read

Brain on Fire: Puzzling brain disease could now be better diagnosed and treated

A rare autoimmune disorder popularized by the autobiography and movie "Brain on Fire" is triggered by an attack on NMDA receptors. The disease occurs when antibodies attack NMDA receptors in the brain, leading to memory loss, intellectual changes, seizures, and death.

This image shows microglia passing from the CNS to PNS

Featured Neuroscience Open Neuroscience Articles

·April 7, 2019·4 min read

Microglia, cells thought restricted to central nervous system, are redefined in new study

In response to injury, microglia cross the spinal boundary from the central nervous system to the peripheral nervous system. While in the PNS, microglia provide the function of clearing cellular debris at the point of injury, then return to the CNS in an altered state. Researchers propose this could account for some damage associated with neurodegenerative diseases.

Featured Neurology Open Neuroscience Articles

·January 20, 2019·3 min read

Targeting ‘Hidden Pocket’ For Treatment of Stroke and Seizure

Study reveals a motif on the 93-series compound fits into a tiny pocket within the NMDA receptor. The findings could lead to new treatment options for stroke and seizures, researchers report.

Featured Neurology Open Neuroscience Articles

·January 7, 2019·4 min read

New Key Mechanism of Epileptic Seizures Revealed

According to a new mathematical model of seizures, only the conductivity of the AMPA receptors in neurons in the temporal lobe significantly change, leading to stronger excitation and synaptic signals.

Featured Neuroscience Psychology

·August 29, 2018·7 min read

Ketamine’s Antidepressant Effects Tied to Opioid System in the Brain

Researchers report ketamine's antidepressive effects require activation of opioid receptors in the brain. The study highlights the interaction between depression, pain and opioid addiction.

Featured Neuroscience

·August 11, 2018·4 min read

Early Sensory Stimulation is Critical for the Development of Sensory Networks

A new study reports sensory stimulation during the first two weeks of life is critical for establishing brain networks that help map sensation.

Featured Neuroscience

·August 10, 2018·4 min read

PSD as a Molecular Platform For Understanding Synapse Formation and Plasticity

A new study reports that both in solution and on supported membrane bilayers, multivalent interaction networks formed by major excitatory postsynaptic density scaffold proteins led to formation of PSD-like assemblies via phase separation.

Featured Neuroscience Open Neuroscience Articles Psychology

·August 10, 2018·4 min read

Targeting a Brain Mechanism Could Help Treat Aggression

Researchers have identified some of the key neurobiological mechanisms that help keep aggression under control. The findings could help develop targeted treatments to help those with aggressive problems associated with psychological disorders.

Featured Neurology

·August 1, 2018·4 min read

Alzheimer’s Drug May Stop Disease If Used Before Symptoms Appear

Researchers report memantine, an FDA approved drug, may not only alleviate symptoms of mild Alzheimer's disease, but could also prevent progression of the disease if used before symptoms appear.

Featured Neuroscience

·July 23, 2018·5 min read

How Experience Changes Basics of Memory Formation

Researchers report animals with previous conditioned experiences form memories using different plasticity mechanisms to naive subjects, even if they are about to learn the same thing.

Autism Featured Genetics Open Neuroscience Articles

·June 26, 2018·3 min read

New Insight Into How Autism Might Develop in the Brain

Researchers have identified a new molecular mechanism that may play a role in the development of autism.

Featured Neuroscience Psychology

·June 22, 2018·4 min read

Ketamine Acts Fast to Treat Depression and Its Effects Last, But How?

Researchers explore the mechanisms behind ketamine's effectiveness at treating depression. The study reports the long lasting effects of ketamine may be due to G proteins timing in moving back to lipid rafts.

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NMDA

Brain on Fire: Puzzling brain disease could now be better diagnosed and treated

Microglia, cells thought restricted to central nervous system, are redefined in new study

Targeting ‘Hidden Pocket’ For Treatment of Stroke and Seizure

New Key Mechanism of Epileptic Seizures Revealed

Ketamine’s Antidepressant Effects Tied to Opioid System in the Brain

Early Sensory Stimulation is Critical for the Development of Sensory Networks

PSD as a Molecular Platform For Understanding Synapse Formation and Plasticity

Alzheimer’s Drug May Stop Disease If Used Before Symptoms Appear

How Experience Changes Basics of Memory Formation

New Insight Into How Autism Might Develop in the Brain

Ketamine Acts Fast to Treat Depression and Its Effects Last, But How?

Unleashing the Mind: The Neuroscience of Meditation and its Impact on Memory

Unveiling the Complexity of Musical Taste: Subgenres and Preferences Explored

Researchers Release The Most Detailed Fruit Fly Nerve Cord Connectome

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