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This shows a male and female head with brains drawn on

·July 20, 2020·4 min read

Highly Reproducible Sex Differences in Aspects of Human Brain Anatomy

Analysis of over 2,000 brain scans revealed evidence of highly reproducible sex differences in the volume of different regions of the brain. On average, females had greater cortical volume in the medial and lateral prefrontal cortex, orbitofrontal cortex, superior temporal cortex, and lateral parietal cortex. Males had increased volume in the ventral temporal and occipital brain regions. Gene expression data suggest the potential role of sex chromosomes that contribute to the differences.

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·June 13, 2020·4 min read

Brain cells can harbor and spread HIV virus to the body

Astrocytes harbor HIV and spread the virus to CD4+ T cells that traffic the virus out of the brain and into other organs. HIV moves via this route, even when the virus is suppressed with cART.

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·April 20, 2020·4 min read

Infant temperament predicts personality more than 20 years later

The temperament of your infant could determine their personality and social behaviors almost three decades later, a new study reports. Infants with higher levels of behavioral inhibition at 14 months grew up to be more reserved and introverted as adults.

This is a drawing of a brain and brain waves

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·February 10, 2020·5 min read

Neural signature identifies people likely to respond to antidepressant medication

A new machine-learning algorithm that analyzes EEG data can identify reliable and robust neural signatures associated with antidepressant treatment response.

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·November 18, 2019·4 min read

Side effects mild and brief with single antidepressant dose of intravenous ketamine

The side effects of administering ketamine to treat major depressive disorder are mild and persist for no longer than four hours, researchers report. Most of the side effects peaked within an hour of treatment, and many patients reported the effects as being significantly reduced two hours post ketamine administration.

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·October 25, 2019·4 min read

Schizophrenia risk gene linked to cognitive deficits

SETD1A, a gene associated with schizophrenia, stunts the growth and branching of dendrites and reduces the number of dendritic spines. Reinstating the normal expression of SETD1A in mouse models restored working memory function.

This shows the location of the amygdala and hippocampus in the brain

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·October 2, 2019·4 min read

Male/female differences in the development of brain hubs involved in memory and emotion

A new neuroimaging study reveals sex-based differences in the development of the hippocampus and amygdala. The findings may shed light on sex-based differences in the emergence of mental health disorders the occur during adolescence and early adulthood.

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·September 23, 2019·4 min read

Gene regulators work together for oversized impact on schizophrenia risk

Using CRISPR to alter the expression of four schizophrenia implicated genes which harbor expression quantitative trait loci, researchers were able to mirror gene expression changes seen in postmortem brains of those suffering from three mental health disorders.

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·April 11, 2019·3 min read

Ketamine reverses neural changes underlying depression-related behaviors: Mouse study

The formation of prefrontal cortex dendritic spine formation sustains the remission of depressive related symptoms and behaviors following ketamine treatment by restoring lost spines.

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·March 13, 2019·5 min read

Differences in brain activity in children with anhedonia

Using fMRI to examine the brains of children while resting, researchers discover anhedonia is associated with hyperconnectivity between the cingulo-opercular network and ventral striatum.

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·February 18, 2019·4 min read

Neuromelanin-Sensitive MRI Identified As a Potential Biomarker for Psychosis

A new study reports neuromelanin sensitive MRI is able to measure dopamine function associated with psychosis.

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·January 17, 2019·7 min read

Surprising Role of the Cerebellum in Reward and Social Behaviors

Researchers reveal the role the cerebellum plays in helping to control the brain's reward system. The researchers identified a direct connection from the cerebellum to the ventral tegmental area. The study may shed new light on neural networks associated with social dysfunction.