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neuropharmacology

Featured Neurology Neuroscience Open Neuroscience Articles

·September 22, 2021·3 min read

Nasal Drugs Show Promise for Slowing Parkinson’s Disease Progression

Two new intranasal drugs slow inflammation and stop the spread of alpha-synuclein in mouse models of Parkinson's disease. The drug also improved gait and balance in the animals. If the results are able to be replicated in humans, researchers say the drugs could be hailed as a "remarkable advance" in the treatment of Parkinson's disease.

This shows a finger touching a picture of a brain

Featured Neuroscience Open Neuroscience Articles

·September 16, 2021·3 min read

Drug Targets for Memory Enhancement

Researchers identified specific receptors for acetylcholine that reroute information flow through memory circuits in the hippocampus. The findings could have implications for the development of drugs to help enhance or protect memory from diseases associated with cognitive decline.

Brain Cancer Featured Neurology Neuroscience

·August 27, 2021·4 min read

Treatment That May Be Viable For Human Brain Cancer Discovered

A new STING treatment induces immunological responses that allow the immune system to fight otherwise immunological resistant glioblastoma cancer cells, researchers report.

Featured Neuroscience Psychology

·August 23, 2021·5 min read

Prozac Changes Fat Composition of the Brain

Prozac reduced polyunsaturated fatty acid lipid concentrations in the brains of juvenile macaque monkeys.

Featured Neuroscience Psychology

·August 21, 2021·5 min read

Neuroactive Steroids May Induce Prolonged Antidepressant Effects by Altering Brain States

Allopregnanolone, a neuroactive steroid used in the treatment of postpartum depression, alters neural communication in the basolateral amygdala, an area of the brain associated with emotion and mood regulation. The drug may alter the network associated with chronic stress, which may explain its persistent antidepressant effect.

Featured Genetics Neurology Neuroscience

·August 19, 2021·5 min read

Disturbed Circadian Rhythm May Be Associated With Alzheimer’s Disease

Long-term circadian rhythm disruptions induce Alzheimer's disease-like pathology in rats, which can be reversed by administering fluoxetine. Additionally, elevated levels of amyloid beta and circadian rhythm disruptions can trigger each other, leading to the cascade of neurological symptoms of dementia.

Featured Neurology Neuroscience

·August 12, 2021·3 min read

Some Diabetes Drugs Reduce Risk and Symptoms of Alzheimer’s

Dipeptidyl peptidase-4 inhibitors, a class of drug that reduces blood sugar in type 2 diabetes, were associated with less amyloid accumulation in the brain and slower cognitive decline in patients.

This shows amyloid beta in a staining sample

Featured Neurology Neuroscience

·August 7, 2021·3 min read

Miniature Brain Models Developed to Study the Causes of Alzheimer’s and Test Drugs in Development

Researchers have developed a new brain organoid model to study the mechanistic causes of Alzheimer's disease and test dementia drugs currently in development.

Featured Neuroscience Open Neuroscience Articles Psychology

·August 7, 2021·4 min read

Nutritional Supplements Could Help Treat PTSD

Combining two natural products that modulate the epigenome, researchers believe they have identified a feasible approach to reversing symptoms of PTSD in animal models that could be effective in humans.

Featured Neuroscience Psychology

·July 31, 2021·5 min read

Dual-Drug Therapy Shows Promise for Treating Alcohol Use Disorder

A new dual-drug therapy for alcohol use disorder appears to be effective and has fewer side effects or complications compared to other medications used to treat AUD.

Featured Neurology Neuroscience

·July 31, 2021·5 min read

Drug That Slows Progression of ALS May Provide the Same Benefit for People With Alzheimer’s

Riluzole, a drug commonly prescribed to slow the progression of ALS, appears to slow brain metabolic decline and improve cognitive performance in those with mild Alzheimer's disease.