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neuropharmacology

·December 11, 2021·5 min read

Malfunctioning Brain Cells a Potential Target for Alzheimer’s Treatment

Researchers have identified a rare population of potentially toxic senescent cells that may be a novel target for Alzheimer's disease therapies.

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Featured Neurology Neuroscience

·December 9, 2021·5 min read

Are Scientists Homing in on a Cure for Parkinson’s Disease?

Researchers have refined a molecule that shows promise for the prevention of Parkinson's disease.

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Featured Neurology Neuroscience

·December 6, 2021·5 min read

Erectile Dysfunction Drug a Possible Candidate for Alzheimer’s Treatment

Sildenafil, an FDA-approved drug to treat erectile dysfunction (Viagra) and pulmonary hypertension, appears to be a promising candidate to prevent and treat Alzheimer's disease.

This shows single cell RNA sequencing of the microglia response in a mouse model of Alzheimer's

Featured Genetics Neurology Neuroscience

·December 1, 2021·4 min read

Targeting the Brain’s Immune Cells May Help Prevent Alzheimer’s Disease

A drug currently being tested in cancer clinical trials appears to prevent dysfunction in an immune cell signaling pathway associated with Alzheimer's disease. Blocking the pathway could prevent Alzheimer's from developing and slow the progression of symptoms for those who already have the disease.

Brain Cancer Featured Neurology Neuroscience

·November 26, 2021·4 min read

Drug Designed for Alzheimer’s Disease May Hold Promise for Treating Glioblastoma

A class of drugs called BACE1 inhibitors, originally designed to treat Alzheimer's disease, shows potential for the treatment of glioblastoma brain cancer.

Featured Neuroscience Psychology

·November 19, 2021·5 min read

Psychedelics Show Promise in Treating Mental Illness

A growing body of evidence suggests psychedelics including psilocybin and LSD show promise in providing lasting relief from symptoms for those suffering some mental health disorders. Researchers found DOI, a similar drug to LSD, reduced negative behavioral responses following fear triggers in mouse models of anxiety.

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Featured Neurology Neuroscience Open Neuroscience Articles Pain

·November 16, 2021·4 min read

Single Molecule Within a Specific Plant Used by Native Americans Can Treat Both Pain and Diarrhea

The extracts of certain plants long used by Native Americans as topical analgesics activate the KCNQ2/3 potassium channel. The compounds provide pain relief and prevent diarrhea.

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Featured Neurology Neuroscience Open Neuroscience Articles

·November 15, 2021·5 min read

New Approach Provides Potential Vaccine and Treatment for Alzheimer’s

A newly developed antibody-based treatment and protein-based vaccine reduced Alzheimer's symptoms in mouse models, researchers report.

Featured Neurology Neuroscience

·November 10, 2021·3 min read

Repurposing Cancer Drug to Treat Alzheimer’s in Those With Genetic Risk Factors

Dasatinib, an FDA-approved drug for chronic myeloid leukemia, and an experimental drug for liver cancer reduced neuroinflammation, tau phosphorylation, and amyloid secretion in cell cultures of post-mortem brain samples of those with the APOE4 Alzheimer's associated gene.

Featured Neuroscience Psychology

·November 9, 2021·5 min read

New Imaging Biomarkers That Predict Antidepressant Response Identified

Combining neuroimaging and artificial intelligence, researchers identified novel brain signatures unique to the response of each antidepressant.

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Brain Cancer Featured Neurology Neuroscience

·November 6, 2021·6 min read

Combining Two Old Therapies Packs a Powerful Punch Against Medulloblastoma

Combining Disulfiram, a medication commonly used to treat chronic alcoholism, with copper ions kills medulloblastoma cancer cells and prevents new ones from growing.