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neuroinflammation

·December 30, 2020·5 min read

Study Uncovers Blood Vessel Damage & Inflammation in COVID-19 Patients’ Brains but No Infection

Researchers found hallmarks of damage caused by thinning and leaky blood vessels in brain samples of people after contracting COVID-19, but saw no evidence of SARS_CoV_2 in the tissue samples. Findings suggest the damage was not caused by a direct viral attack on the brain, but by the body's immune response to the infection.

Featured Neuroscience Psychology

·November 16, 2020·3 min read

Parasite Infection Discovery Could Assist Mental Health Treatments

Behavioral changes in those with T.gondii infection could be linked to lower levels of norepinephrine. Norepinephrine also controls inflammation. Both neuroinflammation and norepinephrine are associated with a range of psychiatric disorders including schizophrenia and ADHD.

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·November 4, 2020·6 min read

The Gut Trains the Immune System to Protect the Brain

IgA cells that originate in the gut play a role appear to have neuroprotective properties against diseases associated with neuroinflammation, such as meningitis.

Brain Cancer Featured Neurology Neuroscience

·October 28, 2020·4 min read

Cancer Cells Mediate Immune Suppression in the Brain

Myeloid cells can suppress the immune response, allowing breast cancer cells to metastasize in the brain and form secondary tumor sites.

Featured Neurology Neuroscience

·October 20, 2020·4 min read

Anti-Inflammatory Therapy Shows Promise in Slowing Progression of Multiple Sclerosis

A new intranasal delivery system shows promise in reducing neuroinflammation and slowing the progression of multiple sclerosis.

Featured Neurology

·October 14, 2020·2 min read

Links Between Inflammation and Parkinson’s Disease Highlighted

Parkinson's patients carrying mutations in PINK1 and Parkin genes have increased levels of circulating interleukin 6 and mitochondrial DNA. The findings strengthen a link between genetic risk factors from Parkinson's disease and inflammation.

Featured Neuroscience

·September 30, 2020·4 min read

Novel Role of Microglia as Modulators of Neurons in the Brain Is Discovered

Researchers have identified a bio-chemical circuit that supports neuron-microglia communication. When neurons are active, they release ATP. Microglia sense extracellular ATP and the compound draws the immune cell toward the neuron.

Neuroscience

·September 2, 2020·4 min read

Inflammation Linked to Alzheimer’s Disease Development

IFITM3, a protein that plays a role in the immune response to pathogens, also plays a key role in the accumulation of amyloid-beta plaques. As IFITM3 directly affects plaque formation, researchers suggest both viral and bacterial infections could increase the risk of Alzheimer's development.

Featured Neurology Open Neuroscience Articles

·August 7, 2020·4 min read

Key to Dialogue Between Brain Cells to Protect Against Stroke Discovered

DHA treatment reduced the size of the damaged brain area and initiated a repair mechanism in animal models of stroke. DHA affected the levels of MANF and TREM2, two proteins critical for communication between brain cells.

Featured Neurology Open Neuroscience Articles

·July 8, 2020·5 min read

Delirium, Rare Brain Inflammation and Stroke Linked to Covid-19

Coronavirus infection can lead to an array of neurological complications, including delirium, stroke, and a rare, often fatal neuroinflammatory condition called ADEM. The neurological complications did not always correlate with the severity of respiratory symptoms. In some patients, brain inflammation was likely caused by an immune response to COVID-19, suggesting the neurological damage may be a result of immune system activation rather than the virus itself.

Featured Neurology Neuroscience Psychology

·May 15, 2020·6 min read

The Potential of COVID-19 to Infect the Brain

From losing the sense of taste or smell to developing an increased risk of stroke, researchers investigate both the known and potential long-term implications of COVID-19 infection in the brain.

Featured Neurology Neuroscience

·May 11, 2020·4 min read

3D brain-like tissue model links Alzheimer’s disease with herpes

A 3D human tissue culture model demonstrated a possible causal relationship between Alzheimer's disease and herpes simplex virus 1 (HSV-1) infection. 40 Alzheimer's associated genes were over-expressed in the HSV-1 infected brain tissue, including genes associated with the production of amyloid-beta.