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neuroinflammation

·December 29, 2019·7 min read

Drugs that quell brain inflammation reverse dementia

Older mice given anti-inflammatory medication were better able to learn new tasks and became almost as adept at learning as mice half their age.

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·December 20, 2019·3 min read

Scientists discover medicinal cannabis substitute for treating Parkinson’s disease

HU-308, a cannabis substitute, can reduce L-dopa induced dyskinesia in Parkinson's patients.

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·October 21, 2019·3 min read

Pregnancy stress triggers immune response that may contribute to postpartum depression

Chronic stress during pregnancy increases neuroinflammation. The immune changes may create circumstances in the brain, which increase susceptibility to postnatal depression.

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·October 7, 2019·3 min read

Surprise contributor to multiple sclerosis identified

Oligodendrocyte progenitor cells (OPCs) actively contribute to neuroinflammation associated with multiple sclerosis.

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·October 1, 2019·3 min read

A brain protein that could put the brakes on Alzheimer’s

Reducing the expression of the protein TOM1 in mouse models of Alzheimer's disease increased the pathology, exacerbated cognitive problems, and raised levels of inflammation in the brain. Restoring TOM1 reversed the effects. Findings suggest a new therapeutic target for treating dementia.

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·September 13, 2019·3 min read

Acute cerebellar inflammation and hyperexcitability induces ‘depression-like’ behavior

Acute inflammation of the anterior cerebellum resulted in depression-like symptoms in rodent models. Suppressing microglia helped reduce hyperexcitability and symptoms of depression.

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·September 9, 2019·3 min read

High-fat diets affect your brain, not just your physical appearance

High-fat diets are not only bad for your waistline, they are also bad for your brain health. A new study reveals high-fat diets contribute to hypothalamic inflammation which occurs long before symptoms of obesity arise.

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·August 29, 2019·3 min read

The ‘inflammation’ of opioid use: Research correlates inflammation in the brain and gut to negative emotional state during opioid withdrawal

Inflammation caused by opioid use to both the brain and gut may exacerbate symptoms of negative emotions associated with withdrawal. Targeting the inflammation could help alleviate the negative experiences of opioid withdrawal and prevent dependence.

Featured Neurology Neuroscience

·August 22, 2019·3 min read

Treating inflammation with inflammation

Ter119, an inflammatory antibody, has the potential to treat inflammation caused by autoimmune diseases, according to the findings of a new rodent study.

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·August 20, 2019·4 min read

Is pollution linked to psychiatric disorders?

Poor air quality has been linked to higher rates of bipolar disorder and major depressive disorder. Exposure to air pollution during the first ten years of like is also associated with a more than two-fold increased risk of schizophrenia and personality disorders.

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·August 20, 2019·4 min read

Alzheimer’s drug reverses brain damage from adolescent alcohol exposure

Donepezil, a drug routinely administered to slow cognitive decline in Alzheimer's disease, shows promise in treating damage caused to the brain by adolescent alcohol exposure. The drug reverses neuroinflammation and neuron damage in rats exposed to alcohol during adolescence.

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·August 18, 2019·3 min read

Immune system and mental health are connected

Researchers explore the link between the immune system and mental health disorders. Cytokines appear to play a critical role in the development and progression of mental illness. They question if administering prednisolone, a steroid that curbs inflammation, can have a beneficial effect on treating and preventing mental health problems.

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