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neuroinflammation

Featured Neuroscience Open Neuroscience Articles

·August 20, 2019·4 min read

Alzheimer’s drug reverses brain damage from adolescent alcohol exposure

Donepezil, a drug routinely administered to slow cognitive decline in Alzheimer's disease, shows promise in treating damage caused to the brain by adolescent alcohol exposure. The drug reverses neuroinflammation and neuron damage in rats exposed to alcohol during adolescence.

This shows a depressed looking person sitting on some steps

Featured Neurology Neuroscience Psychology

·August 18, 2019·3 min read

Immune system and mental health are connected

Researchers explore the link between the immune system and mental health disorders. Cytokines appear to play a critical role in the development and progression of mental illness. They question if administering prednisolone, a steroid that curbs inflammation, can have a beneficial effect on treating and preventing mental health problems.

Featured Neurology Neuroscience

·July 11, 2019·3 min read

Raising eyebrows on neuroinflammation: Surprising role of ‘skin plumping’ hyaluronic acid

Hyaluronic acid, a substance naturally produced by the human body and a popular additive in cosmetics that boast plumper skin, may be a useful tool in treating neuroinflammation.

Featured Genetics Neurology Neuroscience

·July 11, 2019·4 min read

‘Crosstalk’ between genes promotes brain inflammation in Alzheimer’s

Findings could help in the development of treatments to prevent brain inflammation associated with Alzheimer's disease.

This shows a man with light radiating out of his head

Auditory Neuroscience Featured Neurology Neuroscience Open Neuroscience Articles

·June 18, 2019·3 min read

Reducing brain inflammation could treat tinnitus and other hearing loss-related disorders

Rodent study reveals noise-induced hearing loss is associated with elevated expression of proinflammatory cytokines and microglia activation in the primary auditory cortex. Pharmacologically depleting microglia helps prevent tinnitus in mice with noise-induced hearing loss.

Featured Neuroscience

·June 4, 2019·3 min read

How chronic inflammation may drive down dopamine and motivation

Computational model sheds light on the impact chronic, low-grade inflammation has on the mesolimbic dopamine system and motivational impairments.

Featured Neuroscience Psychology

·May 15, 2019·3 min read

Inflammation induces anhedonia in women but not men

Inflammation appears to reduce reward response in females. Reduced activity in the brain's reward system is a key component of anhedonia, the loss of enjoyment in activities, a core feature of depression. The findings may explain why depression is more prevalent in women than in men.

This shows the outline of a head and brain

Featured Neurology Neuroscience Open Neuroscience Articles

·May 14, 2019·4 min read

Probiotic-derived molecule may suppress fatal brain inflammation

Capsular polysaccharide A (PSA), an envelope molecule, may help to boost the immune system and protect against potentially fatal neuroinflammation associated with Herpes Simplex Encephalitis (HSE). Mice given PSA survived exposure to a lethal herpes simplex viral infection, while those not treated with the probiotic did not, despite both groups being treated with a common antiviral used to treat HSE.

Featured Genetics Neurology Neuroscience

·May 13, 2019·3 min read

How mutations lead to neurodegenerative disease

Genetic mutations which lead to abnormal RNA in regions of repeat DNA sequences set off anti-viral like inflammatory responses. This leads to apoptosis and ultimately trigger the onset of neurodegenerative diseases.

This shows the outline of two heads and neurons

Featured Genetics Neurology Neuroscience

·May 6, 2019·3 min read

Detailed brain map uncovers hidden immune cells that may be involved in neurodegenerative disorders

Using mouse models, researchers have developed a comprehensive map of the brain's immune cells. The study found microglia in the choroid plexus showed a similar activation state as microglia that come into contact with Amyloid deposits.

Featured Genetics Neurology Neuroscience

·May 1, 2019·5 min read

Restoring brain function in mice with symptoms of Alzheimer’s disease

Senolytic drugs administered to mice reduced senescent cells around amyloid plaques by more than 90% and decreased neuroinflammation by 50%. Mice treated with the drug combination also showed improvements in spatial memory, compared to other Alzheimer's model mice who received no treatment. The findings could have positive implications for the treatment of Alzheimer's disease in people with the condition.

Brain Cancer Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·April 30, 2019·3 min read

New technique may improve detection and treatment of advanced brain cancer

Researchers discovered changes in thousands of genes induced by the tumor microenvironment. The study may help in identifying new biomarkers for the early detection, and subsequent treatment, of brain cancers.

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neuroinflammation

Alzheimer’s drug reverses brain damage from adolescent alcohol exposure

Immune system and mental health are connected

Raising eyebrows on neuroinflammation: Surprising role of ‘skin plumping’ hyaluronic acid

‘Crosstalk’ between genes promotes brain inflammation in Alzheimer’s

Reducing brain inflammation could treat tinnitus and other hearing loss-related disorders

How chronic inflammation may drive down dopamine and motivation

Inflammation induces anhedonia in women but not men

Probiotic-derived molecule may suppress fatal brain inflammation

How mutations lead to neurodegenerative disease

Detailed brain map uncovers hidden immune cells that may be involved in neurodegenerative disorders

Restoring brain function in mice with symptoms of Alzheimer’s disease

New technique may improve detection and treatment of advanced brain cancer

Taming Tumor Chaos: Researchers Uncover Key to Improving Glioblastoma Treatment

Hippocampus Predicts Rewards by Reorganizing Memories

Memory Rewritten: Study Finds No Clear Line Between Episodic and Semantic Retrieval

Brain Stimulation Method Can Evaluate Consciousness in Alzheimer’s Disease

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