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neurodegenerative diseases

Featured Neurology Neuroscience Open Neuroscience Articles

·March 11, 2020·4 min read

Common muscle relaxant given via nose shows potential to treat Alzheimer’s

Dantrolene, a common muscle relaxant, shows promise in the treatment of Alzheimer's disease. Mice administered the drug intranasally had higher concentrations of the medicine in their brains, and for longer periods, than those who received it orally. The drug has been shown to help inhibit or slow the progression of several neurodegenerative diseases.

Featured Neurology Neuroscience

·March 11, 2020·5 min read

New target for Parkinson’s therapies identified

Two regions outside of the non-amyloid-beta-component play a critical role in controlling amyloid formation of alpha-synuclein.

This shows microglia, neurons and plaques

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·March 10, 2020·4 min read

Stimulating immune cells to protect against Alzheimer’s

Stimulating activation of microglia may help eliminate Alzheimer's associated plaques, thus helping to prevent the progression of the neurodegenerative disease.

This shows brain activity from the study

Featured Neurology Neuroscience

·March 2, 2020·3 min read

Sleeping sheep may offer clues to human brain disease

Monitoring sleep spindles in sheep may one day translate to sleep based diagnosis of neurodegenerative diseases in humans.

This shows a head made of grass and one made of dried dirt

Featured Neurology Neuroscience

·February 27, 2020·4 min read

The Brain and Climate Change

Increased heat stress as a result of global warming will have a detrimental effect on health and productivity, researchers warn. One major concern is the impact climate change will have on the health of multiple sclerosis patients, due to the clear link between heat and worsening symptoms of the disease.

This shows a person holding a drawing of a heart and brain on a scale

Featured Neurology Neuroscience Open Neuroscience Articles

·February 25, 2020·4 min read

A weak heart also damages the brain

Heart insufficiency has a negative impact on gray matter in the brain. Weak heart function was linked to decreased gray matter in areas of the brain associated with memory and learning, including the hippocampus and parietal medial cortex. This may increase the risk of Alzheimer's disease.

Featured Neurology Neuroscience

·February 24, 2020·3 min read

Transcranial magnetic stimulation shows promise in treating stroke, dementia, and migraines

Transcranial magnetic stimulation (TMS) shows promise in diminishing the effects of early dementia and proves a safe and effective method for treating acute migraine and PPA.

Featured Neurology Neuroscience Open Neuroscience Articles

·February 23, 2020·4 min read

Iron in brain shows cognitive decline in people with Parkinson’s

The measure of iron in the brain may help doctors predict which patients with Parkinson's disease are most likely to develop dementia.

Featured Neurology Neuroscience Open Neuroscience Articles

·February 20, 2020·4 min read

Language disorders as indicators of the diagnosis and progression of Huntington’s disease

Study reports it may be possible to detect the onset and progression of Huntington's disease through linguistic changes in patients. Linguistic impairments often begin before the onset of other Huntington's symptoms.

Featured Neurology Neuroscience

·February 18, 2020·5 min read

Parkinson’s biomarker may originate in gut

Using mouse models, researchers seeded alpha-synuclein aggregates in gut neurons and discovered the clumps can travel to neurons in the brain.

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Featured Neurology Neuroscience

·February 18, 2020·2 min read

Number of people with dementia set to double by 2050

Researchers report the number of people diagnosed with Alzheimer's disease and other dementias will double over the next thirty years.

Featured Neurology Neuroscience

·February 17, 2020·4 min read

Beta-arrestin-2 increases neurotoxic tau driving frontotemporal dementia

The protein beta-arrestin-2 increases tau tangle accumulation in Alzheimer's disease and frontotemporal dementia but interfering with the removal of excess tau from the brain.