Chronic stress causes autophagy in adult hippocampal neural stem cells. This results in a decline of hippocampal neurogenesis. Cognitive deficits and mood disorders that arise as a result of chronic stress are a result of autophagic death of hippocampal neural stem cells.
The FGF signaling pathway is an important extracellular regulator in the fate of neural stem cells switching from neurons to astrocytes in the cerebral cortex.
Eating processed food which contains Propionic Acid (PPA) during pregnancy may affect neural stem cell development in the fetal brain. Excessive PPA reduces the number of neurons and over-produces glial cells, causing inflammation. Additionally, PPA shortens neural pathways. The combination of damaged pathways and reduced neurons may be associated with behavioral deficits associated with ASD.
Awakening dormant stem cells could stimulate the growth of new neurons. The findings could have significant implications for the treatment of neurodegenerative diseases.
A new study reveals maternal diet during pregnancy can have dramatic implications for fetal brain development and can impact short term memory in adults.
Researchers report distant molecular mechanisms can generate the same features in different neurons. The findings shed new light on how brain cells develop.
A new study challenges conventional belief that myelin can inhibit neuronal growth. Researchers report rat myelin stimulated axon outgrowths in neural precursor cells, and human iPSCs.