FeaturedGeneticsNeurosciencePsychology·March 3, 2023·3 min readA Blood Factor Involved in DepressionIn adults, levels of GDF11, a gene that is key to the regeneration of murine neural stem cells, are inversely related to depressive episodes. Administering the GDF11 proteins to aging mice reduced depressive states and improved cognition.Read More
FeaturedGeneticsNeuroscienceOpen Neuroscience Articles·March 1, 2023·4 min readHow to Generate New Neurons in the BrainAfter discovering the importance of cell metabolism in neurogenesis, researchers were able to increase the number of neurons in the brains of adult and elderly mice.Read More
FeaturedGeneticsNeurologyNeuroscience·June 17, 2022·4 min readNeurons and Glia Collaborate to Drive Neural Regeneration Following Brain InjuryStudy reveals how neurons and glial cells contribute to drive neurodegeneration following brain injury.Read More
FeaturedGeneticsNeuroscienceOpen Neuroscience Articles·June 3, 2022·6 min readKey Factor in Neocortex Development DiscoveredA new study sheds light on how the neocortex in the human brain develops.Read More
Brain CancerFeaturedGeneticsNeuroscience·May 11, 2022·4 min readKey Protein Identified for Brain Stem Cell LongevityINSR, a protein essential for insulin activity, plays a critical role in stem cell longevity. Additionally, inactivating INSR in glioblastoma brain cancer stem cells inhibits the growth of primitive tumor forming cells.Read More
FeaturedGeneticsNeuroscienceOpen Neuroscience Articles·January 20, 2022·6 min readOld Neurons Can Block Neurogenesis in MiceHippocampal neurogenesis and cognitive function were improved in aging mice by destroying senescent cells in the aging stem cell niche.Read More
FeaturedGeneticsNeurologyNeuroscience·March 1, 2021·6 min readIndividualized Brain Cell Grafts Reverse Parkinson’s SymptomsGrafting neurons derived from a monkey's own stem cells reversed the debilitating and mental health symptoms associated with Parkinson's disease. The treatment shows promise for alleviating the symptoms of Parkinson's in humans.Read More
FeaturedGeneticsNeuroscience·February 27, 2021·3 min readReactivating Aging Stem Cells in the BrainIncreasing lamin B1 levels in aging mice resulted in neural stem cell division and an increase in the number of new neurons.Read More
FeaturedGeneticsNeuroscience·February 22, 2021·4 min read‘Mini Brain’ Organoids Grown in Lab Mature Much Like Infant BrainsBrain organoids, or mini-brains, created from human stem cells appear to develop in much the same way as a human brain. The organoids follow an internal clock that guides their maturation in sync with the timeline for human brain development.Read More
FeaturedGeneticsNeuroscienceOpen Neuroscience Articles·February 20, 2021·4 min readHow a Longevity Gene Protects Brain Stem Cells From StressFOXO3, a gene linked to longevity in humans, protects neural stem cells from the negative effects of stress.Read More
FeaturedGeneticsNeuroscienceOpen Neuroscience Articles·February 11, 2021·3 min readWake-up Call for Neural Stem CellsThe brain enzyme Pr-set7 activates dormant neural stem cells.Read More
FeaturedGeneticsNeuroscience·August 13, 2020·4 min readBecoming a Nerve Cell: Timing Is of the EssenceMitochondria regulate how neural stem cells become neurons during brain development. The findings may help explain how humans developed larger brains during evolution and how mitochondrial defects lead to some neurodevelopmental disorders.Read More
