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          mTORC1

          This shows a dna strand
          AutismFeaturedNeuroscience
          ·November 1, 2022·4 min read

          Study Offers New Insights Into Genetic Mutations in Autism Disorders and Points to Possible Treatments

          Mutations of the PTEN gene cause neurons to grow to twice the size and form four times the number of synaptic connections to other neurons as a normal neuron. Removing the RAPTOR gene, an essential gene in the mTORC1 signaling pathway, prevents the neuronal and synaptic overgrowth associated with PTEN mutations. Using Rapamycin to inhibit mTORC1 recues all the changes in neuronal overgrowth.
          Read More
          This shows genomic sequencing
          AutismFeaturedGeneticsNeuroscience
          ·October 21, 2019·4 min read

          New therapeutic strategy may help reverse autism behavioral abnormalities

          Genetically silencing mTORC2 in mouse models prolonged lifespan, suppressed seizures, increased long-term memory, and reduced autism-like behaviors.
          Read More
          This shows how NV-5138 affects dendrites
          FeaturedNeuroscienceOpen Neuroscience ArticlesPsychology
          ·April 17, 2019·3 min read

          New drug mimics benefits of ketamine for depression

          NV-5138, a small molecule drug that mimics the action of ketamine, provides fast-acting antidepressant responses in rodent models of depression. The drug is currently undergoing Phase 1 testing in humans.
          Read More
          Image shows glass of whiskey.
          FeaturedNeurosciencePsychology
          ·September 11, 2017·5 min read

          Protein Links Alcohol Abuse and Changes in Brain’s Reward Center

          A new Neuron study reports blocking the action of the mTORC1 protein causes mice to stop problem drinking behaviors. The findings could help develop new treatments for addictive behaviors in people.
          Read More
          Image shows a tomato, a note book and a tape measure.
          FeaturedNeuroscienceOpen Neuroscience Articles
          ·May 23, 2017·4 min read

          Why Our Brain Cells May Prevent Us From Burning Fat When We Diet

          Researchers have identified a mechanism that allows the body to adapt to a low caloric intake and limits weight loss.
          Read More
          Image shows pills.
          FeaturedNeurologyOpen Neuroscience Articles
          ·May 8, 2017·4 min read

          Lithium May Prevent Neuron Damage In TBI Patients

          According to researchers, lithium, a drug commonly used to treat bipolar disorder, and rapamycin can help to protect neurons from further damage in those with TBI.
          Read More
          Diagram of mice.
          FeaturedNeuroscience
          ·April 27, 2016·5 min read

          Restoring Memory Formation Following Sleep Deprivation in Mice

          A new study reports sleep deprivation is tied to an impairment of protein production in the hippocampus.
          Read More
          Image shows a labelled diagram of mitochondria.
          FeaturedGeneticsOpen Neuroscience Articles
          ·February 4, 2016·4 min read

          Cell Aging Triggered by Mitochondria

          A new study reports mitochondira are major triggers of cell aging.
          Read More
          Image shows Purkinje cells.
          FeaturedGeneticsNeurology
          ·January 7, 2016·4 min read

          Molecular Mechanism For Rare Neurodegenerative Disease Discovered

          A new study identifies a mechanism responsible for the degeneration of Purkinje cells in the cerebellum in Spinocerebellar ataxia type 1, a rare neurodegenerative disease.
          Read More
          Image shows a pregnant woman's belly.
          FeaturedGeneticsNeuroscienceOpen Neuroscience Articles
          ·September 28, 2015·3 min read

          Hormone Adiponectin Could Break Cycle of Obesity

          According to a new study, the hormone Adiponectin can reverse the negative effects of obesity on offspring when infused into the placenta of obese, pregnant mice.
          Read More
          The image shows a single striatal neuron (yellow) transfected with nuclear inclusion (orange) mHtt, other neurons in background (blue).
          FeaturedGeneticsNeurology
          ·January 5, 2015·4 min read

          Animal Study Points to a Treatment for Huntington’s Disease

          Researchers improve motor function and reduce brain shrinkage in animal models of HD by adjusting the levels of a signaling protein.
          Read More
          This image shows the crystallographic structure of the N-terminal region of the human Huntingtin protein with an artificially attached Maltose-Binding protein used for crystallographic purposes.
          FeaturedNeurology
          ·October 28, 2014·3 min read

          Scientists Uncover Major Factor in Development of Huntingtons Disease

          A new study points to a functional connection between mTOR and huntingtin.
          Read More
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          This shows an empty bottle in sand.

          Rising Temperatures Show Climate’s Hidden Impact on Substance Use

          This shows a maze.

          ChatGPT’s Choices: Overload or Overjoyed? Decoding Decision Dynamics

          This shows worms.

          Worms Illuminate Ancient Emotional Mechanisms

          This shows a brain.

          Probing E-Cig and Alcohol’s Joint Assault on the Blood-Brain Barrier

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