A to Z

mTORC1

This image shows a brain with a glass of an alc

·June 24, 2013·4 min read

Addiction Relapse Might Be Thwarted By Turning Off Brain Trigger

Researchers have been able to identify and deactivate a brain pathway liked to memories associated with alcohol cravings in rats.

The image shows a single striatal neuron (yellow) transfected with nuclear inclusion (orange) mHtt, other neurons in background (blue).

Featured Genetics Neurology

·January 5, 2015·4 min read

Animal Study Points to a Treatment for Huntington’s Disease

Researchers improve motor function and reduce brain shrinkage in animal models of HD by adjusting the levels of a signaling protein.

Image shows a labelled diagram of mitochondria.

Featured Genetics Open Neuroscience Articles

·February 4, 2016·4 min read

Cell Aging Triggered by Mitochondria

A new study reports mitochondira are major triggers of cell aging.

This is an MRI scan of a brain with a glioma.

Brain Cancer Featured

·November 7, 2013·3 min read

Common Genetic Pathway Could be Conduit to Pediatric Tumor Treatment

Researchers discover the mTOR pathway is highly active in many cases of pediatric low-grade glioma. Blocking the pathway lead to a decreased growth of the brain tumors.

Autism Neurology

·January 31, 2012·3 min read

Gene Mutation in Autism Found to Cause Hyperconnectivity in Brain’s Hearing Center

Hyperconnectivity triggered by loss of PTEN gene can be blocked by treatment with rapamycin. New research from Cold Spring Harbor...

Featured Genetics Neuroscience Open Neuroscience Articles

·September 28, 2015·3 min read

Hormone Adiponectin Could Break Cycle of Obesity

According to a new study, the hormone Adiponectin can reverse the negative effects of obesity on offspring when infused into the placenta of obese, pregnant mice.

Featured Neurology Open Neuroscience Articles

·May 8, 2017·4 min read

Lithium May Prevent Neuron Damage In TBI Patients

According to researchers, lithium, a drug commonly used to treat bipolar disorder, and rapamycin can help to protect neurons from further damage in those with TBI.

Featured Genetics Neurology

·January 7, 2016·4 min read

Molecular Mechanism For Rare Neurodegenerative Disease Discovered

A new study identifies a mechanism responsible for the degeneration of Purkinje cells in the cerebellum in Spinocerebellar ataxia type 1, a rare neurodegenerative disease.

This shows how NV-5138 affects dendrites

Featured Neuroscience Open Neuroscience Articles Psychology

·April 17, 2019·3 min read

New drug mimics benefits of ketamine for depression

NV-5138, a small molecule drug that mimics the action of ketamine, provides fast-acting antidepressant responses in rodent models of depression. The drug is currently undergoing Phase 1 testing in humans.

The image shows three different images of synaptic connections. The caption best describes the image.

Featured Genetics Psychology

·April 14, 2014·2 min read

New Finding Suggests a Way to Block Stress Damage

The gene REDD1 enables stress to damage neurons and cause depressive behavior, a new study reports.

Autism Featured Genetics Neuroscience

·October 21, 2019·4 min read

New therapeutic strategy may help reverse autism behavioral abnormalities

Genetically silencing mTORC2 in mouse models prolonged lifespan, suppressed seizures, increased long-term memory, and reduced autism-like behaviors.

Featured Neuroscience Psychology

·September 11, 2017·5 min read

Protein Links Alcohol Abuse and Changes in Brain’s Reward Center

A new Neuron study reports blocking the action of the mTORC1 protein causes mice to stop problem drinking behaviors. The findings could help develop new treatments for addictive behaviors in people.

1 2